Overview

V monografii opisany osnovnye polozheniya i metody sovremennoy meditsinskoy genetiki, a takzhe oblasti ikh klinicheskogo ispol'zovaniya. Predstavlena obshchaya kharakteristika nasledstvennykh zabolevaniy, vklyuchaya khromosomnye i monogennye bolezni, klassifitsirovannye po tipam nasledovaniya. Na primere monogennykh miopatiy i serdechno-sosudistykh zabolevaniy rassmotrena vozmozhnost' sistemnoy klassifikatsii nasledstvennykh bolezney. Otdel'naya glava posvyashchena roli geneticheskikh sostavlyayushchikh v etiologii mnogofaktornykh bolezney. Preimushchestva i ogranicheniya patogeneticheskoy klassifikatsii nasledstvennoy i mnogofaktornoy patologii rassmotreny na primere konformatsionnykh i autoimmunnykh zabolevaniy. Podrobno izlozheny geneticheskie osnovy kantserogeneza. Obsuzhdayutsya problemy farmakogenetiki, diagnostiki i profilaktiki, a takzhe lecheniya nasledstvennykh i vrozhdennykh zabolevaniy. Kniga dopolnena obzorom po istorii razvitiya meditsinskoy genetiki v Rossii, a takzhe snabzhena slovarem geneticheskikh terminov. Rukovodstvo prednaznacheno dlya studentov, internov, ordinatorov i aspirantov meditsinskikh VUZov, a takzhe prakticheskikh vrachey, interesuyushchikhsya voprosami meditsinskoy genetiki.

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