Medically Unexplained Symptoms: A Brain-Centered Approach

Author:   Robert W. Baloh, MD, FAAN
Publisher:   Springer Nature Switzerland AG
Edition:   1st ed. 2021
ISBN:  

9783030591809


Pages:   204
Publication Date:   02 December 2020
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Medically Unexplained Symptoms: A Brain-Centered Approach


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Overview

Despite the rapid advances in medical science, the majority of people who visit a doctor have medically unexplained symptoms (MUS), symptoms that remain a mystery despite extensive diagnostic studies. The most common MUS are back pain, abdominal pain, headache, fatigue, and dizziness.  This book addresses the obstacles of managing people with MUS in our modern day society from both a historical and contemporary perspective. Most MUS are psychosomatic in origin, caused by a complex interaction between nature and nurture, between biological and psychosocial factors.  Psychosomatic symptoms are as real and as severe as the symptoms associated with structural damage to the brain.  Unique and concise, the book explores the biological and psychosocial mechanisms, the clinical features, and current and future treatments of common MUS.  Exploring the unsolved in an accessible manner, Medically Unexplained Symptoms invokes the methodologies of medical science, history, and sociology to investigate how brain flaws can lead to debilitating symptoms. 

Full Product Details

Author:   Robert W. Baloh, MD, FAAN
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2021
Weight:   0.454kg
ISBN:  

9783030591809


ISBN 10:   3030591808
Pages:   204
Publication Date:   02 December 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction   Chapter 1. Overview of Medically Unexplained Symptoms                 Pain                 Brain flaws                 Fear                 Anxiety                 Dizziness                 Stress                 Fatigue                 Diagnostic uncertainty   Chapter 2. Early ideas on hysteria                 Hysteria and female sexuality                 Bizarre behaviors                 Hysteria and the occult                 Nerves                 Hysteria, a nervous disorder                 Early treatments of hysteria                 Spinal irritation and the spinal reflex theory                 The attack on the female genitalia                 Hysteria and fasting girls   Chapter 3. The Golden age of Hysteria                 Briquet’s syndrome                 Charcot and his hysterical circus                 Hysteria and hypnosis                 Borderlands of hypnosis                 Nature or nurture                 Ideas about hysteria evolve                 Neurasthenia and neurosis                 Americanitis                 S Weir Mitchell and the Civil War                 The Rest Cure                 S Weir Mitchell, the enigma                 Nerve doctors                 Evolution and the brain   Chapter 4. Psychosomatic illness in the 20th Century                 Freud, the early years                 Breuer’s famous patient, Bertha Pappenheim                 Freud and Breuer’s book on hysteria                 Suppressed memories and childhood sexuality                 Freud’s model of the mind                 Overall impact of psychoanalysis                 Physicians, patients and psychosomatic symptoms                 Common sense psychotherapy                 Alternate medical treatments and suggestibility                 War and Psychogenic Illness                 PTSD the prototypical delayed stress disorder                 Relationship between PTSD and mild traumatic brain injury (mTBI)                 Psychosomatic medicine   Chapter 5. Biological mechanisms of Psychosomatic Symptoms                 The biological link between stress and illness                                 The hypothalamic-sympathetic-adrenal axis                                 The brain’s emotional center, the limbic system                                 The hypothalamic-pituitary-adrenal axis                 Pavlov and neural plasticity                 Hebb’s Synapse                 Molecular mechanisms of brain plasticity                 Stress and the limbic system                                 Nerve growth factors and stress                                 The amygdala-prefrontal cortex connection                 Central sensitization, a model of neuroplasticity                                 The descending pain modulatory system (DPMS)                 Brain neurotransmitters                                 Gamma aminobutyric acid (GABA)                                 Noradrenalin                                 Serotonin                                 Dopamine                                 Cannibinoids                 Stress and human behavior                                 Operant conditioning and behavioral therapy   Chapter 6. Psychosocial mechanisms of psychosomatic Symptoms                 How can beliefs and expectations change brain function?                 Doctor patient relationship and psychosomatic symptoms                 The power of the placebo                 Placebo’s evil twin, nocebo                                 Statins and muscle pain and weakness                                 Glutens and Celiac disease                                 Expectations and beliefs                                 Hyperventilation syndrome                 Idiopathic environmental intolerance and the nocebo effect                                 The Belgium Coca-Cola fiasco                                 Electromagnetic hypersensitivity                                 Infrasound sensitivity                                 Sick building syndrome                 Summary of Idiopathic environmental intolerance mechanisms         Chapter 7. Low back pain, abdominal pain and headache                 Overview of common pain syndromes                 Low back pain                                 Historical perspective                                 Current approach to chronic low back pain                                 Physical activity and expectation                                  Depression and fear avoidance                 Abdominal pain                                 Autonomic nervous system and the gut                                 Irritable bowel syndrome (IBS)                                 Peptic ulcer disease                  Primary headache disorders                 Migraine as a model for psychophysiological illnesses                                          Historical perspective                                 Migraine Auras                                  Early ideas on the cause of migraine                                 Mechanism of the migraine aura                                  Genetic susceptibility to migraine   Chapter 8. Fibromyalgia/Chronic Fatigue Syndrome                 Pain but much more                 Fibromyalgia                                 Tender points                                 Central sensitization to pain                 Repetitive strain injury (RSI)                 Chronic fatigue                 Epidemic and sporadic neuromyasthenia                 Epstein-Barr virus (EBV)                 Chronic fatigue immune dysfunction syndrome (CFIDS)                 Myalgic encephalomyelitis (ME)                 Overlap with depression and other psychogenic illnesses                 Genetics of fibromyalgia and chronic fatigue syndrome   Chapter 9. Chronic dizziness                 Anxiety and Dizziness                 Near faint dizziness and fainting                                 Postural orthostatic tachycardia syndrome (POTS)                                 Dizziness and mass psychogenic illness                 Persistent Postural Perceptual Dizziness (PPPD)                 Migrainous dizziness                 Post Concussion Dizziness                 Sea legs and mal de Debarquement syndrome                 Height vertigo and acrophobia   Chapter 10. Treatment of psychosomatic symptoms                 Lifestyle changes                                 Exercise and the brain                                 Sleep and eating habits                 Mindfulness                 Cognitive Behavioral Therapy                 Internet Directed Therapy                 Drug treatments                 Drugs that increase brain monoamines (antidepressants)                 Drugs that decrease excitatory (glutamate) transmission                                 Antiepileptic drugs                                 Anxiolytic drugs                 Drugs that enhance neuroplasticity and neurogenesis                                 Ketamine, the new “wonder drug”                 Drugs that effect endocannibinoid neurotransmission                 Extracranial Brain stimulation                                 Electroconvulsive therapy (ECT)                                 Transcranial direct current stimulation (tDCS)                                 Transcranial magnetic stimulation (TMS)                 Deep brain stimulation                                 DBS for PTSD                 Future Directions

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Robert W. Baloh MD Distinguished Professor of Neurology David Geffen School of Medicine at UCLA Los Angeles, CA

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