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Overview"Despite the prevalence of both pharmaceutical and behavioral approaches to encourage cessation, over a billion people still indulge in tobacco. Even in the U.S., where tobacco use is considered a clearly treatable and socially regrettable condition, a significant percentage of individuals remain resistant to treatment modalities. It is believed that the problem lies with the availability, the effectiveness, and the tolerance of the treatments. Thus, the development of new and more effective medications for treating nicotine dependence is an area of significant therapeutic importance, and one made increasingly more viable given our rapidly increasing knowledge about the actions of nicotine and tobacco components on the brain. ""We are entering a Renaissance period ! that promises to provide us with improved pharmacological tools to tackle this most serious of worldwide public health problems."" -- from the Preface Medication Treatments for Nicotine Dependence assembles contributions from leading researchers and clinicians to provide the most comprehensive volume on current and future possibilities for addressing nicotine and tobacco dependence with medication. Organized into six sections, this important work covers-- Basic pharmacology and physiology of nicotine and nicotinic receptors First-line medications for nicotine addiction, including NRTs and sustained release bupropion Second-line medications including antidepressants, inhibitors, and antagonists Promising treatments currently in development Special topics such as the combination of medications with behavioral treatments and pharmacogenetic approaches to treatment The text concludes with the presentation of two unique perspectives on the development of medications for nicotine dependence and its implications for clinical practice. Medication Treatments for Nicotine Dependence serves as a useful primer and resource for established investigators, as well as those new to the research; for students from a range of disciplines, including pharmacology, psychology, public health, and medicine; and for those clinicians actively engaged in the treatment of nicotine dependence." Full Product DetailsAuthor: Tony P. George (Yale University School of Medicine, New Haven, CT, USA) , Tony P. George (Yale University School of Medicine, New Haven, CT, USA) , Paul R. Pentel (Hennepin County Medical Center, Minneapolis, MN, USA) , Suchitra Krishnan-SarinPublisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 15.60cm , Height: 2.40cm , Length: 23.40cm Weight: 0.703kg ISBN: 9780849337796ISBN 10: 0849337798 Pages: 327 Publication Date: 28 July 2006 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsPharmacological Effects of Nicotine and Nicotinic Receptor Subtype Pharmacological Profiles. Cellular and Synaptic Effects of Nicotine. Animal Models of Nicotine Addiction. Nicotine Replacement Therapies and Other Nicotinic Strategies. Sustained-Release Bupropion as a Pharmacological Aid to Smoking Cessation.Tricyclic Antidepressants in the Treatment of Nicotine Dependence.Monoamine Oxidase Inhibitors for Smoking Cessation.Opioid Antagonists for the Treatment of Nicotine Dependence. Other Nonapproved Agents for Smoking Cessation.Immunological Approaches to Nicotine Addiction. Glutamatergic Agents for Nicotine Dependence. GABAergic Agents for the Treatment of Nicotine Dependence.Cannabinoid Antagonists.Targeting the Dopamine D3 Receptor for Treatment of Nicotine Dependence. Varenicline: An α4â2 Nicotinic Acetylcholine Receptor Partial Agonist as an Aid to Smoking Cessation.Combining Medications with Behavioral Treatments. Medication Treatments for Nicotine Dependence in Psychiatric and Substance Use Disorders. Pharmacogenetic Approaches to the Treatment of Nicotine Dependence. Neuroimaging of Nicotine Dependence. Suggestions for Future Research. Treatment of Nicotine Dependence.Reviews... this is a book that clinicians as well as researchers will find useful. ... On the whole, individual chapters are well researched and presented, with a wealth of references to back up the prose. ... This book provides an easy way for practitioners to avail themselves of the up-to-date research findings, which they may use in the treatment of nicotine additions. ... This is certainly a book that will be useful to all who are doing research in the area of medication treatments for nicotine dependence, as well as for those who might be prescribing such medications. ... it will also be valuable for those who are offering behavioral treatments and need to know how medications can be incorporated into their treatment plans. ... -John C. Roitzsch, in PsycCritiques, Vol. 52, Release 30, Article 12, July 2007 . . . it can serve as an excellent reference to address questions about the mechanism of action or the pharmacologic rationale for a given therapy. The book is well-organized, so it will be useful as a reference. - Meredith C. McCormack, Pulmonary and Critical Care Medicine, Johns Hopkins University, in Respiratory Care, September 2008, Vol. 53, No. 9 ... this is a book that clinicians as well as researchers will find useful. ... On the whole, individual chapters are well researched and presented, with a wealth of references to back up the prose. ... This book provides an easy way for practitioners to avail themselves of the up-to-date research findings, which they may use in the treatment of nicotine additions. ... This is certainly a book that will be useful to all who are doing research in the area of medication treatments for nicotine dependence, as well as for those who might be prescribing such medications. ... it will also be valuable for those who are offering behavioral treatments and need to know how medications can be incorporated into their treatment plans. ... -John C. Roitzsch, in PsycCritiques, Vol. 52, Release 30, Article 12, July 2007 . . . it can serve as an excellent reference to address questions about the mechanism of action or the pharmacologic rationale for a given therapy. The book is well-organized, so it will be useful as a reference. - Meredith C. McCormack, Pulmonary and Critical Care Medicine, Johns Hopkins University, in Respiratory Care, September 2008, Vol. 53, No. 9 Author InformationTony P. George Tab Content 6Author Website:Countries AvailableAll regions |
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