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OverviewThis fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. Full Product DetailsAuthor: J. David Sweatt (McKnight Brain Institute, Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Edition: 2nd edition Dimensions: Width: 21.60cm , Height: 2.50cm , Length: 27.60cm Weight: 1.440kg ISBN: 9780123749512ISBN 10: 0123749514 Pages: 362 Publication Date: 12 November 2009 Audience: College/higher education , Undergraduate , Postgraduate, Research & Scholarly Replaced By: 9780128142066 Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1. Introduction - the basics of psychological learning and memory theory 2. Studies of human learning and memory 3. Non-associative learning and memory 4. Rodent behavioral learning and memory models 5. Associative learning and unlearning 6. Hippocampal Function in Cognition 7. Long-term Potentiation: A Candidate Cellular Mechanism for Information Storage in the CNS 8. The NMDA Receptor 9. Biochemical mechanisms for information storage at the cellular level 10. Molecular genetic mechanisms for long-term information storage at the cellular level 11. Inherited disorders of human memory – mental retardation syndromes 12. Aging-related memory disorders – Alzheimer’s Disease APPENDIX. The Basics of Experimental DesignReviewsAuthor InformationDavid Sweatt obtained his B.S. in Chemistry from the University of South Alabama before attending Vanderbilt University, where he was awarded a Ph.D. for studies of intracellular signaling mechanisms. He then did a post-doctoral Fellowship at the Columbia University Center for Neurobiology and Behavior, working on memory mechanisms in the laboratory of Nobel laureate Eric Kandel. From 1989 to 2006 he was a member of the Neuroscience faculty at Baylor College of Medicine in Houston, Texas, rising through the ranks there to Professor and Director of the Neuroscience Ph.D. program. Dr. Sweatt's laboratory studies biochemical mechanisms of learning and memory. In addition, his research program also investigates mechanisms of learning and memory disorders, such as mental retardation and aging-related memory dysfunction. He is currently the Evelyn F. McKnight endowed Chairman of the Department of Neurobiology at UAB Medical School, and the Director of the Evelyn F. McKnight Brain Institute at the University of Alabama in Birmingham. He also is a Professor the Departments of Cell Biology, Genetics, and Psychology at UAB. Dr. Sweatt has won numerous awards and honors, including an Ellison Medical Foundation Senior Scholar Award, and election as a Fellow of the American Association for the Advancement of Science. This year he won (along with Michael Meaney and Catherine Dulac) the Ipsen Foundation International Prize in Neural Plasticity, one of the most prestigious awards in his scientific field. From 1998 until 2002 he attended drawing and painting classes at the Glassell School of Art of the Museum of Fine Arts, Houston. As an artist he explores the use of painting as a medium for expressing topics of interest in contemporary biomedical research. In 2009 he published a textbook, Mechanisms of Memory, which is illustrated with original paintings and describes current models for the molecular and cellular basis of memory formation. Tab Content 6Author Website:Countries AvailableAll regions |
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