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OverviewThis work aims to promote an understanding of the pathophysiologic mechanisms mediating renal dysfunction in disease. It also provides a perspective in understanding mechanisms of chemically induced renal injury. Evolving concepts on the pathophysiology of glomerulonephritis, chronic glomerular injury, diabetic nephropathy and acute renal failure are changing the clinical management of these disease states and are fully covered in this work. Topics covered include: machanisms of acute and chronic renal failure; mechanisms of chronic glomerular injury; the role of eicosanoids in renal disease; mechanisms of chemically induced nephrotoxicity; renal drug-metabolizing enzymes in experimental animals and humans; mitrochondrial mechanisms of tubular injury; and reactive oxygen metabolites and iron in toxic acute renal failure. Full Product DetailsAuthor: Robin Goldstein , William O. Berndt , Lawrence H. Lash (Wayne State Univ School of Medicine, Detroit, Michigan, USA) , Joseph V. Bonventre (Massachusetts General Hospital, Charlestown, USA)Publisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 17.80cm , Height: 1.90cm , Length: 25.40cm Weight: 0.908kg ISBN: 9780849388736ISBN 10: 0849388732 Pages: 310 Publication Date: 01 August 1994 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationRobin S. Goldstein Tab Content 6Author Website:Countries AvailableAll regions |