Overview

DNA damage responses are integral to the repair of DNA and initiation of checkpoints that maintain genomic stability.

Full Product Details

Author:   Tanya Paull
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Volume:   v. 4
ISBN:  

9780387691367

ISBN 10:   0387691367
Pages:   250
Publication Date:   01 August 2009
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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Table of Contents

ATR biochemistry.- ATM biochemistry.- ATM biochemistry, Xenopus extracts.- ATR bioschemistry Xenopus extracts.- ATM/ATR signaling related topics and cell assays.- ATM, Brca1 cell based assays.- immunofluorescence-based techniques for looking at DSB signaling.- mouse modles.- mouse models.- mouse models.- checkpoint signaling at replication forks.- checkpoint adaptation.- checkpoint signaling.- chromatin and DSBs.- Brca2, Rad51 biochemistry.- signaling pathways and non-homologous, Xenopus extracts.- DNA PK and ATM DSB recognition.- DNA-PK/Ku DSB recognition.- NEJ,DSBR.- mismatch repair.- mismatch repair.- excision repair.- DSBR.- mismatch repair

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