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Overview"This text summarizes recent progress on the regulation of target gene transcription by steroid hormone receptors. Steroid hormones travel via the blood stream to thier target cells which they enter by diffusion. Steroid hormone receptors exist in these cells in inactive forms either in the cytoplasm or nucleus. Upon binding to their respective hormone ligands, the receptors go through a ""transformation"" step and become activated. The activated receptor can then activate transcription of hormone response genes." Full Product DetailsAuthor: M-.J. Tsai , Bert W. O'MalleyPublisher: Taylor & Francis Inc Imprint: CRC Press Inc Weight: 0.675kg ISBN: 9781570590931ISBN 10: 1570590931 Pages: 115 Publication Date: 01 January 1994 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsSteroid receptor superfamily; receptor-DNA interaction; mechanism of ligand activation of steroid receptors - in vitro - DNA binding and transcription; mechanism of ligand activation of steroid receptors - mechanisms of ligand activation; phosphorylation of steroid receptor; role of receptor in development and differentiation; orphan receptors.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |