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OverviewNovel Approaches into the Origins of Neurodevelopmental Disorders: The Fetal Physiology Foundation Over the past two decades, autism, a neurodevelopmental disorder that is defined by behavior and was once believed to be rare, became recognized in increasing numbers of children and recently received distinction as an “epidemic” [1]. While numbers of affected children have steadily increased, our knowledge is still ins- ficient to explain autism’s diverse causes and broad range of presentations. Despite remarkable progress in research, available medical diagnostic testing applies only to a small minority of affected children. Thus, scientifically based explanations with which physicians can diagnose and treat the majority of children with autism and advise their parents are quite limited. Our society and scientific community were unprepared for the rise in autism, which explains our present inability to understand most of its causes. Researchers in neurodevelopmental disorders have long been aware of other disorders that, despite extensive efforts, have not yielded clear genetic or environmental origins, and autism has become symbolic of the need for new approaches to research into these complex conditions. Although autism has captured our attention in recent years, the prevalence of other neurodevelopmental disorders such as attention de- cit hyperactivity disorder (ADHD) and bipolar disorder, among others, also has been increasing [2–4]. Full Product DetailsAuthor: Andrew W. Zimmerman , Susan L. ConnorsPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2010 ed. Dimensions: Width: 15.50cm , Height: 1.00cm , Length: 23.50cm Weight: 0.285kg ISBN: 9781489981615ISBN 10: 1489981616 Pages: 166 Publication Date: 20 October 2014 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsBrave New World: The Intrauterine Environment as the Biological Foundation for the Lifespan.- In the Beginning.- Maternal Influences on the Developing Fetus.- Implications of Maternal Programming for Fetal Neurodevelopment.- Maternal Thyroid Function During Pregnancy: Effects on the Developing Fetal Brain.- Obstetric Factors Related to Perinatal Brain Injury.- Activation of the Maternal Immune System as a Risk Factor for Neuropsychiatric Disorders.- Prenatal Infections and Schizophrenia in Later Life – Focus on Toxoplasma gondii.- Maternally Acting Alleles in Autism and Other Neurodevelopmental Disorders: The Role of HLA-DR4 Within the Major Histocompatibility Complex.ReviewsFrom the reviews: This interesting book examines an extremely pertinent topic in obstetrics, the gene-environment interplay and its effects on the developing human brain. ... Clearly the authors have done a good job of reviewing relevant literature as well as provoking new ideas. ... The audience includes clinicians and scientists interested in the fetal origin of disease. ... this is an interesting book about a worthwhile topic in obstetrics. ... it is a worthwhile contribution to the field. (Anthony Shanks, Doody's Review Service, December, 2010) Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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