Overview

In the decade since publication of the first edition of Crystallographic Methods and Protocols the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I, Preparation and Crystallization of Macromolecules is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while Volume 2, Structure Determination, covers both computational methods for characterizing crystals and solving structures.

Full Product Details

Author:   Sylvie Doublie
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2007 ed.
Volume:   364
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   1.310kg
ISBN:  

9781588299024

ISBN 10:   1588299023
Pages:   284
Publication Date:   05 February 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Cryocrystallography of Macromolecules.- Determination of Reaction Intermediate Structures in Heme Proteins.- Annealing Macromolecular Crystals.- First Analysis of Macromolecular Crystals.- X-Ray Data Collection From Macromolecular Crystals.- Characterizing a Crystal From an Initial Native Dataset.- Molecular Replacement.- Phase Determination Using Halide Ions.- The Same But Different.- Substructure Determination in Multiwavelength Anomalous Diffraction, Single Anomalous Diffraction, and Single Isomorphous Replacement With Anomalous Scattering Data Using Shake-and-Bake.- Substructure Determination in Isomorphous Replacement and Anomalous Diffraction Experiments.- Automated Structure Solution With autoSHARP.- to Macromolecular Refinement.- Quality Control and Validation.- Crystallographic Software.

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