Overview

A highly disabling infectious disease in developing countries, leprosy, or Hansen’s disease, is caused by Mycobacterium leprae, and is still very relevant for the human community due to its transmissible nature, variable presentation and composite clinical picture. Early identification of leprosy and Buruli ulcer (also caused by a Mycobacterium, M. ulcerans) is critical to prevent spreading and patient disability and to establish appropriate therapy. This richly illustrated, completely revised second edition of Leprosy and Buruli Ulcer describes the characteristic signs of both these diseases, and contents include abnormalities of the skin, nerves, eyes, hands, feet, testes and bone. It also presents the latest diagnostic tools to identify and quantify organ damage to enable readers to recognize and treat this composite systemic disorder, which can represent a true medical emergency if affecting eyes, nerves, and kidneys. Further, it includes additional chapters on leprosy in childhood, prophylaxis and vaccines. For both leprosy and Buruli ulcer, this handy guide helps practitioners and nursing personnel to spot the different clinical manifestations, make a prompt diagnosis and apply effective treatment of both these diseases.

Full Product Details

Author:   Enrico Nunzi ,  Cesare Massone ,  Françoise Portaels
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   2nd ed. 2022
Weight:   1.092kg
ISBN:  

9783030897062

ISBN 10:   3030897060
Pages:   570
Publication Date:   27 June 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Foreword.- Preface.- Part I Leprosy: General Section.- 1. History and Phylogeography of Leprosy.- 2.   Microbiology of Mycobacterium leprae.- 3. Genetics of Leprosy.- 4. Host Response to Mycobacterium leprae.- 5.   Pathogenesis of Leprosy.- 6. Classification of Leprosy.- Part II Leprosy: Patient’s Examination.- 7. Leprosy Patient History.- 8. Laboratory  Investigations in Leprosy.- Part III Skin.- 9. Physical Examination in Leprosy: Skin.- 10. Clinical Features of Leprosy.- 11. Lucio–Latapí Leprosy.- 12. Histopathology of the Skin in Leprosy [FP1] .- 13.   Differential Diagnosis of Leprosy: Skin.- Part IV  Leprosy and Nerves.- 14. Peripheral Nerves in Leprosy.- 15. The Leprosy Neuropathy.- 16. Primary Neural Leprosy.- 17. Chronic Neuropathic Pain in Leprosy.- 18. Electrodiagnostic Studies in Leprosy.- 19. Imaging in Leprosy.- 20. Differential Diagnosis of Leprosy: Nerves.- Part V   Reactions in Leprosy.-21. Reactions in Leprosy.- 22. Lucio’s Phenomenon in Leprosy.- Part VI  Leprosy: Systemic Involvement.- 23. Ocular Involvement in Leprosy.- 24. Otolaryngological Manifestations of Leprosy.- 25.   Other Organs involved in Leprosy.- Part VII Patient’s Management in Leprosy.- 26. Diagnostic Work-Up of Leprosy.- 27. Drugs in Leprosy.- 28. Treatment and Prophylaxis of Leprosy.- 29. Prognosis of Leprosy.- 30.  Neurolysis in Leprosy.- 31. Prevention of Disability and Ulcer Care in Leprosy.- 32. Surgical and Social Rehabilitation in Leprosy.- Part VIII   Leprosy and Community.- 33. Leprosy in Pregnancy.- 34. Leprosy in Childhood.- 35. Leprosy and HIV/AIDS Co-infection.- 36. Epidemiology  of  Leprosy.- 37. Leprosy Control.- 38. The Leprosy Mailing List.- Part IX Buruli Ulcer: General Section.- 39. History and geographic distribution of Buruli ulcer.- 40. Microbiology of Mycobacterium ulcerans.- Part X Buruli Ulcer: Patient’s Examination.- 41. Laboratory Investigations in Buruli ulcer.- 42. Clinical Features of Buruli ulcer.- 43. Differential Diagnosis of Buruli ulcer.- Part XI    Buruli Ulcer: Patient’s Management.- 44. Diagnostic Work-up of Buruli ulcer.- 45.  Treatment of Buruli ulcer.- 46. Rehabilitation in Buruli ulcer.- Part XII    Buruli Ulcer and Community.- 47. Epidemiology of Buruli ulcer.- 48. Buruli ulcer Control.- Subject Index.

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Author Information

Professor Enrico Nunzi graduated with honors and specialized in dermatology and syphilography, medical microbiology, dermatology and tropical medicine at the University of Genoa (Italy). He has been Director of the Institute of Dermatology at Loja Technical University Hospital (Ecuador) since 2012. Before that he was Director of the Social Dermatology Unit at S.Martino Hospital and of the Skin Immunopathology Service. Author of over 130 publications in Italian and Spanish, he has worked for the governmental health services of the Democratic Republic of Congo as the Medical Director of the health sector at Kimbau Hospital, as a Research Fellow at the Dermatology Department of the University of Amsterdam, and as Director of the Genoa University Postgrad School of Leprology and Tropical Dermatology. Cesare Massone is an Associate Professor of Dermatology and Venereology, and Medical Director of the Dermatology Unit-Ospedali Galliera in Genova, Italy. After graduating with honors and receiving board certification, he was made an Associate Professor of Dermatology at the Medical University of Graz. His areas of research interest include dermoscopy and melanoma, cutaneous lymphomas, leprosy & tropical dermatology, psoriasis & biologicals therapies, dermatopathology, and teledermatology. Dr. Massone is the author of over 200 publications, including books (WoS HI 34). Regularly presenting at international congresses, he was awarded the Pathnet grant from the French Ministry for Research, and the AESCA Award of the Austrian Society of Dermatology in 2005. Professor Françoise Portaels was Head of the Mycobacteriology Unit, Department of Microbiology, Institute of Tropical Medicine (Belgium). Her areas of expertise include microbiology and epidemiology. She is a Professor Emeritus of the Free University of Brussels (VUB), Belgium and of the Institute of Tropical Medicine Antwerp, Belgium and has a extensive experience in teaching and headinglab research. Member of various academies and societies, including the  International Union Against Tuberculosis (UNION), Belgian Royal Academy of Medicine, Belgian Royal Academy of Oversees Sciences and the American Society of Tropical Medicine and Hygiene. She was awarded the Follereau-Damien and the American Society of Tropical Medicine prizes. She has authored over 400 publications and edited 5 books (WoS HI 32), and has participated in countless field activities, international courses and missions.

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