Overview

For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.

Full Product Details

Author:   Didier Trono
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2002
Volume:   261
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.421kg
ISBN:  

9783642626678

ISBN 10:   364262667
Pages:   260
Publication Date:   17 November 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

List of Contents.- Molecular Biology of Lentivirus-Mediated Gene Transfer.- HIV-1-Derived Lentiviral Vectors.- Lentiviral Vectors Derived from Simian Immunodeficiency Virus.- Nonprimate Lentiviral Vectors.- Production of Lentiviral Vectors.- Biosafety Issues in Lentivector Production.- Lentiviral Vector Targeting.- Integration Site Selection by Lentiviruses: Biology and Possible Control.- Improving the Post-Transcriptional Aspects of Lentiviral Vectors.- Lentiviruses as Vectors for CNS Diseases.- Lentiviral Vectors for the Gene Therapy of Lympho-Hematological Disorders.- Lentiviral Vectors for Gene Therapy of HIV-Induced Disease.- Opportunities for the Use of Lentiviral Vectors in Human Gene Therapy.

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