Overview

Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. In this book, the authors present current research in the study of the structure, biological activity and role in disease of laminins. Topics include the key roles of laminins from embryos to adult skeletal muscle; Laminin-332 and integrins; anosmin-1 and galectin-1 as laminin interactors in nervous system development and pathology; loss of laminin alpha two; role of laminin in epithelial morphogenesis in the liver; laminins in uterine remodelling and embryo development during pregnancy; human gingival laminin-332 degradation by oral bacteria; and laminins as a modulator of the axonal response to guidance cues.

Full Product Details

Author:   Demetrius C Adams ,  Emil O Garcia
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.00cm
Weight:   0.458kg
ISBN:  

9781626185685

ISBN 10:   1626185689
Pages:   159
Publication Date:   19 June 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In stock  
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Table of Contents

Preface; Laminins: Key Roles from Embryos to Adult Skeletal Muscles; Laminin-332 & Integrins: Signaling Platform for Cell Adhesion & Migration & its Regulation by N-Glycosylation; Anosmin-1 & Galectin-1 as Laminin Interactors in Nervous System Development & Pathology; A Potential Role of Laminins & 37 kDa Laminin Receptor Precursor (LRP)/67 kDa Laminin Receptor (LR) in Disease; Loss of Laminin Alpha Two; Roles of Laminins in Epithelial Morphogenesis in the Liver; Role of Laminin on Uterine Remodeling & Embryo Development during Pregnancy; Human Gingival Laminin-332 Degradation by Oral Bacteria; Commentary: Laminins as a Modulator of the Axonal Response to Guidance Cues; Index.

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