Overview

Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadenedour understanding of nephron development and maintenance as well as the diseases related to these processes.  

Full Product Details

Author:   Rachel K. Miller
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2017
Volume:   60
Weight:   5.796kg
ISBN:  

9783319846507

ISBN 10:   3319846507
Pages:   372
Publication Date:   21 July 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part A Model Systems of Kidney Development and Disease.- 1 Drosophila Malpighian tubule: A model for understanding kidney development, function and disease.- 2 Zebrafish pronephros development.- 3 Zebrafish as a model of kidney disease.- 4 Use of Xenopus frogs to study renal development/repair.- Part B Cell Renewal, Differentiation and Fate in Nephrogenesis.- 5 Tissue-specific p53 functions during kidney development.- 6 Growth factor regulation in the nephrogenic zone of the developing kidney.- 7 Development and diseases of the collecting ductsystem.- 8 Origin and function of the renal stroma in health and disease.- Part C Nephron Morphogenesis and Maintenance.- 9 Imaging, analysing and interpreting branching morphogenesis in the developing kidney.- 10 Genetic syndromes affecting kidney development.- 11 Primary cilia in cystic kidney disease.- 12 Inflammation and fibrosis in polycystic kidney disease.- 13 Epithelial to mesenchymal transition (EMT) andendothelial to mesenchymal transition (EndMT): Role and implications in kidney fibrosis.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions