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OverviewThe scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume.The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures.The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis. Full Product DetailsAuthor: National Research Council , National Research Committee on Risk Assessment Methodology , Committee on Risk Assessment Methodology National Research CouncilPublisher: National Academies Press Imprint: National Academies Press ISBN: 9781280211584ISBN 10: 128021158 Pages: 356 Publication Date: 01 January 1993 Audience: General/trade , General Format: Electronic book text Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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