Overview

The structures of sugars attached to cells and proteins have been investigated by biochemists for more than a hundred years. The discipline of glycobiology has emerged more recently, as key principles about the biological functions of these complex sugars have been established and their importance for the study of cell biology and immunology has become apparent. Introduction to Glycobiology is the first textbook to present an introduction to the essential elements of glycobiology that is readily accessible to undergraduates and other non-specialists. It focuses on coherent stories about what sugars do for cells and organisms. The importance of glycosylation in protein secretion and stability, cell-cell adhesion and signalling, and innate and adaptive immunity are emphasised. The ways in which glycobiology explains human disease are discussed throughout the book in order to place the subject in a biomedical context. The book is illustrated throughout with all new custom-drawn figures. The simple organisation, highlighted terms and annotated key reference lists make the text readable and accessible. Companion Web Site All the figures from the book will be available to download free from the companion web site at http://www oup.com/uk/best.textbooks/biochemistry/glycobiolo gy/. A sample chapter will be available on line from 1 August 2002.

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9780199258680

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Maureen Taylor gained her BSc from King's College, University of London and went on to study for her PhD at the University of London. She was a Postdoctoral Research Fellow at Columbia University and is currently University Research Lecturer at the Glycobiology Institute in the Department of Biochemistry, and Fellow and Tutor of Biochemistry at Exeter College, University of Oxford. Kurt Drickamer studied for his BS at Stanford University, and then his PhD at Harvard. He was the Helen Hay Whitney Postdoctoral Research Fellow at Duke University and Cold Spring Harbor Laboratory before being appointed Assistant Professor of Biochemistry, University of Chicago and then Associate Professor of Biochemistry, Columbia University. He is currently Professor of Biochemistry and Wellcome Principal Research Fellow at the Glycobiology Institute in the Department of Biochemistry, University of Oxford.

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