Overview

This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalling pathways that affect tumour development. Current therapeutic strategies are reviewed, along with a discussion of methods for tumour detection and biomarker identification. Finally, the impact of whole genome sequencing is discussed, bringing students up to date with key recent developments in the field. From basic principles to insights into cutting-edge research, this book will enable the reader to move into the cancer field with confidence.

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9781139012904

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Reviews

'Robin Hesketh has produced a remarkable introduction to cancer biology which covers all of the key areas of current knowledge and brings them up to date to current research concepts and developments remarkably. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field … The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology … it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so.' Peter Selby, Director, Leeds Institute of Molecular Medicine 'The structure of the book is clear and well organized. The author writes well, giving excellent explanations of concepts ranging from basic principles to cutting-edge research. The book is a valuable resource for introducing lower-level students to the biology of cancer. Highly recommended.' H. Zhou, Choice

'Robin Hesketh has produced a remarkable introduction to cancer biology which covers all of the key areas of current knowledge and brings them up to date to current research concepts and developments remarkably. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field ... The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology ... it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so.' Peter Selby, Director, Leeds Institute of Molecular Medicine

'Robin Hesketh has produced a remarkable introduction to cancer biology which covers all of the key areas of current knowledge and brings them up to date to current research concepts and developments remarkably. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field ... The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology ... it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so.' Peter Selby, Director, Leeds Institute of Molecular Medicine 'The structure of the book is clear and well organized. The author writes well, giving excellent explanations of concepts ranging from basic principles to cutting-edge research. The book is a valuable resource for introducing lower-level students to the biology of cancer. Highly recommended.' H. Zhou, Choice

'Robin Hesketh has produced a remarkable Introduction to Cancer Biology which covers all of the key areas of current knowledge and brings them up to date to current research concepts and developments remarkably. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field. ... The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology. ... it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so.' Peter Selby, Director of the Leeds Institute of Molecular Medicine

'Robin Hesketh has produced a remarkable introduction to cancer biology which covers all of the key areas of current knowledge and brings them up to date to current research concepts and developments remarkably. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field ... The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology ... it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so.' Peter Selby, Director, Leeds Institute of Molecular Medicine 'The structure of the book is clear and well organized. The author writes well, giving excellent explanations of concepts ranging from basic principles to cutting-edge research. The book is a valuable resource for introducing lower-level students to the biology of cancer. Highly recommended.' H. Zhou, Choice Cancer biology and cancer medicine are broad and extensive fields with fast moving research developing new knowledge of many aspects of cancer. Modern technologies are increasing the pace of acquisition of new knowledge and contributing to real progress in managing patients. Robin Hesketh has produced a remarkable Introduction to Cancer Biology which covers all of the key areas of current knowledge and brings them up to date with current research concepts and developments. He writes in an accessible way that will be valuable for students fresh to biology but also produces a book that will be very useful to experienced biologists and physicians who want to have to hand a broad overview of this fast moving and diverse field. The structure of the book is clear and informative and encompasses critically important biological knowledge from the level of the cell to population studies in epidemiology. The appendices are very useful providing ready access to information on most common cancer and most of the major tabulations of existing knowledge that we may need. In the era of internet access and publication databases, it is very challenging to introduce a book which is really useful both for new students and established practitioners. Robin Hesketh has succeeded remarkably well in doing so. Professor Peter Selby, Director of the Leeds Institute of Molecular Medicine The structure of the book is clear and well organized. The author writes well, giving excellent explanations of concepts ranging from basic principles to cutting-edge research. The book is a valuable resource for introducing lower-level students to the biology of cancer. Highly recommended. H. Zhou, Seton Hall University for Choice Magazine

Author Information

Robin Hesketh has been a member of the Biochemistry Department at the University of Cambridge for over twenty-five years. He has taught at all undergraduate levels from first-year medicine to fourth-year biochemistry on a wide range of cell and molecular biology topics with a particular focus on cancer. His major research area is the development of anti-angiogenic strategies for the treatment of cancer. He is also the author of the popular science book Betrayed by Nature: The War on Cancer (2012).

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