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OverviewAutoimmune diseases, which affect 5 to 10 percent of the population, are as unpredictable in their course as they are paradoxical in their cause. They produce persistent suffering as they follow a drawn-out, often lifelong, pattern of remission and recurrence. Multiple sclerosis, lupus, rheumatoid arthritis, and type 1 diabetes - the diseases considered in this book - are but a handful of the conditions that can develop when the immune system goes awry. Intolerant Bodies is a unique collaboration between Ian Mackay, one of the prominent founders of clinical immunology, and Warwick Anderson, a leading historian of twentieth-century biomedical science. The authors narrate the changing scientific understanding of the cause of autoimmunity and explore the significance of having a disease in which one's body turns on itself. The book unfolds as a biography of a relatively new concept of pathogenesis, one that was accepted only in the 1950s. In their description of the onset, symptoms, and course of autoimmune diseases, Anderson and Mackay quote from the writings of Charles Dickens, Edgar Allan Poe, Joseph Heller, Flannery O'Connor, and other famous people who commented on or grappled with autoimmune disease. The authors also assess the work of the dedicated researchers and physicians who have struggled to understand the mysteries of autoimmunity. Connecting laboratory research, clinical medicine, social theory, and lived experience, Intolerant Bodies reveals how doctors and patients have come to terms, often reluctantly, with this novel and puzzling mechanism of disease causation. Full Product DetailsAuthor: Warwick Anderson (Professorial Research Fellow, University of Sydney) , Ian R. MackayPublisher: Johns Hopkins University Press Imprint: Johns Hopkins University Press Dimensions: Width: 14.00cm , Height: 1.60cm , Length: 21.60cm Weight: 0.318kg ISBN: 9781421415338ISBN 10: 142141533 Pages: 264 Publication Date: 10 January 2015 Recommended Age: From 17 Audience: General/trade , College/higher education , General , Tertiary & Higher Education Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsForeword, by Charles E. Rosenberg Introduction: Thinking Autoimmunity 1. Physiology with Obstacles 2. Immunological Thought Styles 3. A Sense of Unlimited Possibilities 4. The Science of Self 5. Doing Biographical Work 6. Reframing Self Afterword: Becoming Autoimmune, or Being Not Acknowledgments Notes Bibliography IndexReviewsAnderson and Mackay's engaging survey is a studious examination of autoimmune diseases, and a humble admission that their cures remain stubbornly elusive. Publishers Weekly This is a fascinating read... A solid choice for academic science and health sciences collections. Library Journal Anderson and Mackay's engaging survey is a studious examination of autoimmune diseases, and a humble admission that their cures remain stubbornly elusive. Publishers Weekly This is a fascinating read... A solid choice for academic science and health sciences collections. Library Journal A magisterial, historically rich biography of autoimmunity... Anderson and Mackay reveal an expert understanding of how to use 'lived experience' to bring a biography of disease to life. Personal accounts demonstrate how, as theories about the causes of inexplicable chronic debilitating diseases abounded, the variety of treatments devised to alleviate or 'cure' them expanded. -- Tilli Tansey Nature Succinct, well-written, and informed, Intolerant Bodies narrates the history of immunology through the lens of autoimmune disease... the story told here extends far beyond the topic of attack against self to provide perhaps the best overview of immunity (normal and pathological) available for the general reader. Metascience Anderson and Mackay's engaging survey is a studious examination of autoimmune diseases, and a humble admission that their cures remain stubbornly elusive. Publishers Weekly This is a fascinating read... A solid choice for academic science and health sciences collections. Library Journal A magisterial, historically rich biography of autoimmunity... Anderson and Mackay reveal an expert understanding of how to use 'lived experience' to bring a biography of disease to life. Personal accounts demonstrate how, as theories about the causes of inexplicable chronic debilitating diseases abounded, the variety of treatments devised to alleviate or 'cure' them expanded. -- Tilli Tansey Nature Author InformationWarwick Anderson is an Australian Research Council laureate fellow and a professor in the Department of History and the Center for Values, Ethics, and the Law in Medicine at the University of Sydney. He is the author of The Collectors of Lost Souls: Turning Kuru Scientists into Whitemen, also published by Johns Hopkins. Ian R. Mackay is a research professor in the Department of Biochemistry and Molecular Biology at Monash University. He is the coauthor of Autoimmune Diseases: Pathogenesis, Chemistry, and Therapy and the coeditor of The Autoimmune Diseases, fifth edition. Tab Content 6Author Website:Countries AvailableAll regions |
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