Overview

Cancer is a very aggressive disease and currently it has been considered a challenge to oncologists and cancer patients worldwide. Nowadays, several therapeutic strategies had improved toward last decades. Surgery is many times still the best curative treatment, mainly in early stage disease. However, Radiotherapy and chemotherapy acquired a main role in this scenario. Target therapies were introduced for medical oncology practice and are demonstrating a hallmark of a new era in cancer treatment. More recently, immunotherapy has been considered the novel cornerstone in cancer treatment. The 2nd edition of the International Manual of Oncology Practice (iMOP) emerged after the great success of the iMOP 1st edition as a reference for medical oncologists and medical residents in the field. In this edition, several chapters were revised and its addresses from the molecular issues of cancer sciences to the clinical practice in medical oncology. In addition, multiple choice questions and clinical cases were included in the main chapters in order to improve the reader learning. The book focuses systemic treatments in many areas of medical oncology, such as breast cancer, gastrointestinal, thoracic, urological oncology, head and neck tumors, bone tumors, sarcomas and palliative care. The topics herein discussed will provide the readers a step forward in the medical oncology practice understanding and give facilities for help in cancer patient treatments.   

Full Product Details

Author:   Ramon Andrade De Mello ,  Giannis Mountzios ,  Álvaro A. Tavares
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   2nd ed. 2019
Weight:   2.060kg
ISBN:  

9783030162474

ISBN 10:   3030162478
Pages:   1162
Publication Date:   30 October 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Cancer screening and epidemiology R.A. De Mello ramello@ualg.pt or ramondemello@doctors.org.uk UALG, Portugal 2 Cancer stem cells José Bragança jebraganca@ualg.pt  UALG, Portugal 3 Apoptosis Richard Hill richard.hill@port.ac.uk UALG, Portugal 4 Angiogenesis Patrícia Madureira pamadureira@ualg.pt UALG, Portugal 5 Genetic basis of metastasis Mehmet Gunduz mehmet.gunduz@gmail.com Turgut Ozal University, Turkey 6 Anti-cancer Drugs Wolfgang Link walink@ualg.pt UALG, Portugal 7 Immuno-oncology Pedro Madureira ramondemello@gmail.com ICBAS Portugal 8 Health Econimics Nelson Teich nelsonteich@americasoncologia.com.br Américas Oncologia, Rio de Janeiro, Brazil PART II – SOLID TUMORS THORACIC 9 Non-Small Cell Lung cancer A. Tantraworasin ohm_med@hotmail.com Chiang Mai University, Thailand 10 Small cell lung cancer A. Tantraworasin ohm_med@hotmail.com Chiang Mai University, Thailand 11 Mesothelioma Vangelis Karamitrousis v-a-g-@hotmail.com Alexandroupolis, Greece 12 Thymus Hakaru Tadokoro ramondemello@gmail.com UNIFESP, Brazil BREAST  13 Breast Ines Monteiro ines.pcmonteiro@gmail.com Lausanne, Switezerland GASTROINTESTINAL 14 Oesophageal Karima Oualla karimarauf@hotmail.com Fes, Marroco 15 Gastric Luis Castelo-Branco luismocb@hotmail.com Faro, Portugal 16 Colon Nora Forones noraforones@gmail.com UNIFESP, Brazil 17 Rectal JInhui Zhu ramondemello@gmail.com  China 18 Anal Canal Cancer Hakaru Tadokoro ramondemello@gmail.com UNIFESP, Brazil 19 Small intestine Pedro Aguiar Jr pnajpg@hotmail.com Santo André, Brazil 20 Liver Cancer R. A. DE Mello ramondemello@gmail.com UNIFESP, Brazil 21 Pancreatic Cancer George Antoniou dr.antoniou@gmail.com London, UK GYNECOLOGICAL TUMORS 22 Ovarian Renata Justa renatajusta@gmail.com ICC, Brazil 23 Cervical Alvaro Henrique Ingles Garces alvarohenriq@yahoo.com.br INCA, Brazil 24 Vagina Nikolaou Michail nikolaoumike@hotmail.com Larissa, Greece 25 Gestacional trophoblastic disease Donald Peter Goldstein DGOLDSTEIN@partners.org Boston, MA, USA GENITO-URINARY 26 Prostate Cancer   Arlindo Ferreira ajrsferreira@gmail.com Lisboa, Portugal 27 Renal Cell Carcinoma Fernando Nunes fernando.nunes@clion.com.br Salvador, Brazil 28 Urothelial Cancer Ramy F. Youssef ryaacoub@uci.edu California, USA 29 Germ-Cell Tumors Giannis Mountzios gmountzios@gmail.com Athens, Greece 29.1 Penile Cancer Nikolaos Tsoukalas tsoukn@yahoo.gr London, UK 30 Squamous Head and neck Jean-Pascal Machiels   jean-pascal.machiels@uclouvain.be Brussels, Belgium 31 Thyroid cancer Washington Luiz wwgois@gmail.com Fortaleza, Brazil 32 Parotid Gland Tumors José Aurillo Rocha jaurillo@hotmail.com Fortaleza, Brazil SKIN, SOFT TISSUE, BONE, GIST AND ENDOCRINE 33 Melanoma Paolo Ascierto paolo.ascierto@gmail.com Napoli, Italy 34 Soft Tissue Sarcomas Carlos Marcio carlossmarcio@gmail.com Fortaleza, Brazil 35 Bone Sarcomas Hakaru Tadokoro ramondemello@gmail.com UNIFESP, Brazil 36 GIST R. A. De Mello ramondemello@gmail.com Brazil/Switzerland 37 NET Yim KL yimkl2000@hotmail.com Cardiff, UK 38 Primary brain tumor Hakaru Tadokoro ramondemello@gmail.com UNIFESP, Brazil PART III – HEMATO-ONCOLOGY 39 Acute Lymphoblastic Leukemia Eddy Supriyadi e.supriyadi@gadjahmada.edu   Indonesia 40 Myelodisplastic Syndrome Ronald Feitosa ronaldfpinheiro@uol.com.br Fortaleza, Brazil PART IV – PALLIATIVE CARE AND SUPPORTIVE CARE 41 Metabolic disturbance/paraneoplasic syndromes Carmélia Barreto carmeliabarreto@gmail.com Sao Paulo, Brazil 42 Spinal medular compression Hakaru Tadokoro ramondemello@gmail.com São Paulo, Brazil 43 Superior vena cava syndrome Maria Tolia mariatolia1@gmail.com    Larissa, Greece 44 Febrile neutropenia Bora Lim naborala@gmail.com Texas, USA 45 Chemotherapy-Induced Nausea and Vomiting Rudolph M. Navari rmnavari@gmail.com Indiana University School of Medicine South Bend, USA 46 Asthenia F. Koinis phillipkoinis@gmail.com Athens, Greece 47 Oncological pain R.A. De Mello ramondemello@gmail.com UALG, Portugal 48 Bone Metastases Arlindo Rebelo-Ferreira arjsferreira@gmail.com  Lisbon, Portugal 49 Brain metastasis Tiago Pádua Costa tiagopadua1@hotmail.com São Paulo, Brazil 50 Palliative care Débora Galdêncio debora_galgencio@yahoo.com.br Manaus, Brazil    

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Author Information

Ramon Andrade de Mello, MD, PhD University of Algarve, Portugal Ramon Andrade Bezerra de Mello received the MD degree at the Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil, with MD recognition from University of Lisbon, Portugal, and holds the Certificate in Medical Oncology by passing the European examination of ESMO (European Society for Medical Oncology), Lugano, Switzerland. He completed specialization in medicine and molecular oncology and his PhD in Oncology (lung cancer) at the Faculty of Medicine, University of Porto, Portugal. He also completed a post-doctoral clinical research fellowship in lung cancer clinical trials at the Lung Unit, Royal Marsden NHS Foundation Trust, Chelsea, London, United Kingdom, supported by the ESMO. Currently, he works in the Department of Medical Oncology at the Portuguese Oncology Institute, Porto, Portugal, and he teaches at the Department of Medicine of the University of Porto and School of Medicine, University of Algarve, Faro, Portugal. He is medical director of Oncoclínica/Euroclinics, Porto, Portugal. Prof. de Mello performs both basic and clinical research on angiogenesis, palliative medicine, internal medicine, colorectal cancer and lung cancer; further, he has an active office working. He is editor of 2 books (Tamoxifen Concepts and Cancer: New Paradigms and Vimentin Concepts and Molecular Mechanisms, Nova Science, NY, USA, 2013), author of several scientific articles, chapters and comments on basic and clinical research. He presented more than 50 papers in congresses and conferences in several countries, such as United States, Sweden, Brazil, Portugal and Spain. Furthermore, he serves as editorial board of several reputed scientific journals, such as PLoS ONE, Rare tumors, Oncology Reviews and scientific reviewer of the British Journal of Cancer, Journal of Thoracic Oncology, Annals of Internal Medicine and The Lancet. He participates as expert reviewer of grant applications at the University of Coimbra, Portugal, National Science Centre, Kraków, Poland, and the British Lung Foundation, London, UK. Prof. de Mello is an active member of the ESMO Young Oncologist Committee and consultant at Pfizer gastric cancer advisory board. SHORT CV GIANNIS MOUNTZIOS MD, MSc, PhD Dr Giannis Mountzios was born in Larissa, Greece, in 1974. He obtained his medical degree (MD) from the Aristotle University of Thessaloniki in 1998 with a scholarship from the Greek Ministry of Education and graduated from the Hellenic Military Medical Academy the same year. He completed his residency in Internal Medicine at the Airforce General Hospital of Athens and in Medical Oncology at the University of Athens School of Medicine, “Alexandra” University Hospital (Pr. M.A. Dimopoulos). He then obtained a master (MSc) in translational and clinical research in Oncology from the Institut Gustave-Roussy and the University Paris XI (Paris-Sud), France, in 2007 (Pr. Jean-Charles Soria) and became board-specified in Medical Oncology in 2009. In 2010 he obtained his PhD in Medical Oncology from the University of Athens School of Medicine. He is currently working as a consultant Medical Oncologist at the University of Athens School of Medicine. Dr Mountzios has received fellowships from the American Society of Clinical Oncology (Young Investigator award), the European Society for Medical Oncology (Annual Fellowship for Translational Research in 2005, Annual Fellowship for Clinical Research in 2009) and the Hellenic Society for Medical Oncology (HESMO). He is currently the General Secretary of the board of directors of HESMO, former chair of the HESMO young medical oncologists committee and former member of the steering committee of the young medical oncologists of ESMO. SHORT CURRICULUM VITAE Álvaro Tavares Álvaro A. Tavares, born in 1964, obtained his degree in Biochemistry from the University of Lisbon, Portugal. He later obtained a M.Sc. in Molecular Biology from the New University of Lisbon, and a PhD in Biomedical Sciences from the University of Porto, Portugal. He then moved to Scotland where for five years was a Post-doctoral at the Department of Anatomy and Physiology of the University of Dundee. In 1999, having been appointed professor at the Instituto Superior Técnico , Lisbon, he started his own research group at the Gulbenkian Science Institute. In 2009 he moved to the University of Algarve, to the newly formed Department of Biomedical Sciences and Medicine, where he currently directs the Cell Division and Cancer Biology Research Group. In the course of his research career, Álvaro Tavares has studied proteolytic systems in rat liver mitochondria, proteolysis regulation in differentiation in the plant Lupinus albus, genetic regulation and expression in yeast S. cereviseae, and molecular and genetic characterization of genes required for cell proliferation in Drosophila melanogaster. The underlying theme behind the current work of his laboratory is the basic biology of mitotic cell division, in particular the aspects regulating the formation of a bipolar mitotic spindle and the connection between centrosomes and cytokinesis. The ultimate goal is to understand how modifications of these processes contribute to the transformation of normal into cancer cells. These problems are approached through a combination of biochemical, genetic and cytologic techniques, taking advantage of Drosophila melanogaster genetics and human tissue cultured cells.

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