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OverviewA great deal of new information has been obtained during the past four years, and this monograph provides a clear and well reviewed update on biochemical mechanisms and the results of important new clinical studies using the interferons. Reviews include what is presently known about the biosynthesis, physiological role and mechanisms of action of the interferons (alpha, beta, gamma). New biochemical information on interferon-receptor interactions and signalling pathways is provided. The pharmacokinetic considerations in treating leukemia, lymphoma, myeloma, neuroendocrine tumors and other solid tumors are reviewed with special emphasis on studies of adjuvant chemotherapy in malignancies of the immune system. Full Product DetailsAuthor: Derek CrowtherPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of the original 1st ed. 1991 Dimensions: Width: 21.00cm , Height: 0.40cm , Length: 27.70cm Weight: 0.221kg ISBN: 9783642767890ISBN 10: 3642767893 Pages: 63 Publication Date: 11 January 2012 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsThe Interferons: Their Properties and Clinical Role—An Overview.- Interferons: Biosynthesis, Physiological Roles, Mechanisms of Induction and Response.- The Mechanisms of Action and the Role of Alpha Interferon in the Therapy of Myeloma.- The Role of Interferon in the Management of Low-Grade Lymphoma.- The Role of Interferons in Neuroendocrine Tumours and Aspects of Mechanisms of Action.- The Interferons plus Other Modalities of Cancer Therapy.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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