Innervation of the Mammalian Esophagus

Author:   Winfried Neuhuber ,  M. Raab ,  Hans-Rudolf Berthoud ,  Jürgen Wörl
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2006 ed.
Volume:   185
ISBN:  

9783540292050


Pages:   76
Publication Date:   13 February 2006
Format:   Paperback
Availability:   Out of stock   Availability explained
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Innervation of the Mammalian Esophagus


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Overview

1 Introduction The esophagus is a relatively simple though vital organ. It consists of a two-layered muscular tube whose lumen is lined by squamous strati?ed epithelium. Beyond its role of propelling food from the pharynx to the stomach by a propulsive contraction wave representing the esophageal phase of deglutition (Conklin and Christensen 1994; Jean 2001), it is more and more recognized as a sensory organ from which a variety of respiratory and cardiovascular re?exes can be triggered, thus coop- ating with the larynx in protecting the lower airways from aspiration (Barthelemy et al. 1996; Lang et al. 2002; Lang et al. 2001; Loomis et al. 1997; Medda et al. 2003). In ruminants, there is additional antiperistalsis for regurgitation. During emesis, the esophagus is a merely passive conduit except for some antiperistalsis in its upper part. In the interval between swallows, both oral and aboral ends of the esophagus are tonically closed by the upper and lower esophageal sphincters, UES and LES respectively, while the tubular esophagus is ?accid and partly ?lled with air. Despite this apparent simplicity, neuronal control of esophageal functions is quite complex.

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Author:   Winfried Neuhuber ,  M. Raab ,  Hans-Rudolf Berthoud ,  Jürgen Wörl
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2006 ed.
Volume:   185
Dimensions:   Width: 15.50cm , Height: 0.50cm , Length: 23.50cm
Weight:   0.165kg
ISBN:  

9783540292050


ISBN 10:   3540292055
Pages:   76
Publication Date:   13 February 2006
Audience:   College/higher education ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Introduction.- Muscle layers of the esophagus.- Materials and Methods. Anterograde WGA-HRP tracing from nodose ganglion. Anterograde DiI tracing from thoracic dorsal root ganglia.- Extrinsic innervation. Vagal innervation.- Spinal innervation. Innervation of esophageal sphincters. Swallowing central pattern generator. Cortical representation of the esophagus in human.- Intrinsic innervation. General organization. Enteric coinnervation.- Functional considerations. General remarks. Cooperation between extrinsic and intrinsic systems.- Concluding remarks.- Summary.- References.- Subject Index.

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