Overview

The management of orthopedic infection is an area of growing importance in orthopedic surgery. This text provides a complete overview from basic research to clinical application and future perspectives in the treatment of orthopedic infection emphasizing the role of local therapy. Coverage details the various approaches to the treatment of orthopedic infections, making the book an important tool for the daily practice of its readers.

Full Product Details

Author:   Enzo Meani ,  Carlo Romano ,  Lynn Crosby ,  Gunther Hofmann
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.880kg
ISBN:  

9783540479987

ISBN 10:   3540479988
Pages:   395
Publication Date:   05 February 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Introduction: The social and economical impact of orthopedic infections. Orthopedic device-related infections: Epidemiology and classification of device-related orthopedic infection.- Diagnostic challenges: early and differential diagnosis.- Bacterial strategies of implant colonization and resistance.- Pathologic findings of septic loosening.- Antibiotic prophylaxis in orthopedic surgery.- The limits of systemic antibiotics in device-related infections.- Antibiotic bone cement as a prophylactic means.- The limits of the local antibiotic therapy.- The role of suppressive therapy. Basic research and local antibiotic therapy: PMMA as drug delivery system and in vivo release from spacers.- Problems and pitfalls of antibiotic spacers.- The preformed spacers: from the idea to the realization of an industrial device.- Fatigue and wear characterization of the preformed hip spacer.- Fatigue characterization of the preformed knee spacer.- Surface analysis of the spacer before and after the clinical use.- Bone loss: does the use of the spacer affects it?- Antibiotic impregnated bone grafts - what do we know?- Antibiotic-loaded bone grafts: personal experience.- Bi-physical bone loss and permanent replacement.- Antibiotic loaded cement: from research to clinical evidence. Clinical applications: Hip: The management of infection in THA: an historical excursus.- Girdlestone arthroplasty after hip prosthesis infection - a two stage revision.- One stage cemented revision of septic hip prosthesis.- One stage non-cemented revision of septic hip prosthesis using antibiotic loaded bone graft.- One-stage or two-stage revision: the reason of a choice.-Block spacer vs preformed spacer in two-stage revision.- Two-stage revision with pre-formed hip spacers.-Two stage revision of septic hip prosthesis with uncemented implants.- Long-stem pre-formed spacers followed by uncemented implants: a solution for wide femoral opening or bone loss intwo-stage revision.- Two-stage cemented revision of septic hip implants.- Analysis of the gait in patients with hip spacers. Clinical applications: Knee: Septic knee prosthesis revision: a challenging surgery.- One stage cemented revision of septic knee prosthesis.- Static vs articulating spacers.- Antibiotic-loaded cement spacers for the 2-stage revision of TKR.- Key points in two-stage revision: bone loss, quality of life between stages and surgical approach at second stage.- Two-stage revision with pre-formed knee spacers and modular knee prosthesis.- Arthrodesis for the treatment of severe knee disease.- Arthrodesis and amputation.- Salvage procedures in exposed septic knee prosthesis. Novel applications and perspectives: The management of the shoulder prosthesis infection.- The shoulder spacer as a definitive solution?- The genta-vanco preformed spacer: pharmacological study.- Rationale of nail antibiotic clothing and 'in vivo' animal study.- The use of cemented antibiotic-loaded spacers in post-traumatic bone infections.- The use of antibiotic-impregnated cement in infected reconstructions after resection for bone tumors.- Antibiotic coatings: a new approach to infection prevention in orthopedics.- Local antibiotic therapy: present and future.

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