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OverviewStudy on first degree relatives of Bangladeshi prediabetic subjects explore that they are at increased risk for developing different types of glucose intolerance. Age-matched healthy controls were without any family history of DM or prediabetes. HOMA% B was significantly lower among first degree relatives all types of prediabetic and HOMA% S in only relatives of IFG-IGT subjects were significantly lower compared to controls. BMI values higher than 23 had significantly less insulin sensitivity compared to their counterparts with BMI less than 23. All the relatives showed significantly higher postprandial serum glucose and dyslipidemia was evident as compared to control. So beta cell secretory dysfunction seem to have a genetic origin in first degree relatives of prediabetes and the genesis of the various phenotypes of prediabetes results from a complex interaction between this primary defect and other factors like BMI, body fat mass, early lipid abnormality and waist circumference contributing to insulin resistance. Full Product DetailsAuthor: Sultana Marufa Shefin , Omar FaruquePublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.30cm , Length: 22.90cm Weight: 0.095kg ISBN: 9783659180743ISBN 10: 3659180742 Pages: 56 Publication Date: 14 August 2012 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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