Overview

The discovery of chlorpromazine for the specific treatment of schizophrenic symp­ toms and, later on, of imipramine for the specific treatment of depressive symptoms marked a new milestone in clinical psychiatry and basic neuroscience 40 years ago. The exploration of biochemical mechanisms of action of these psychotropic drugs created new theories on the pathophysiology of psychiatric disorders, such as the dopamine hypothesis of schizophrenia and the catecholamine and serotonin hypotheses of depression. Thus the discovery of these biological treatments had a major impact on natural science-oriented research. Biological psychiatry as we know it today has its origin in these psychopharmacological drugs and influences many disciplines in psychiatry. It was a fortunate coincidence that Hans Hippius, whose 70th birthday we celebrated this year with an international symposium, started his professional career during this time in the 1950S. He was one of the early pioneers in clinical psycho­ pharmacological research and enthusiastic about both the scientific and the thera­ peutic prospects of the new psychotropic drugs. He has worked in this field for more than three decades and has made many lasting contributions to biological psychiatry. Among the many activities, his contributions in the development of the new atypical antipsychotic drug clozapine should be mentioned.

Full Product Details

Author:   M. Ackenheil ,  B. Bondy ,  R. Engel ,  M. Ermann
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1996
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   0.318kg
ISBN:  

9783642646836

ISBN 10:   3642646832
Pages:   187
Publication Date:   27 September 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Neurotransmitter Interactions Important for Schizophrenia.- The Etiology of Affective Illness.- New Findings in the Genetic of Bipolar Illness.- Targeting the Action of Antidepressant Drugs on Second-Messenger Systems.- New Concepts of Schizophrenia Derived from Epidemiological Research.- The Course of Psychiatric Disorders as a Diagnostic Tool.- A Psychonanalytic Model for the Classification of Personality Disorders.- Functional Pathology: An Essential Diagnostic Step in Biological Psychiatric Research.- The Development of Nosological Concepts in Anxiety Disorders.- Classification of the Affective and Related Disorders.- The Ideal Neuroleptic.- Long-Term Treatment of Schizophrenia.- Treatment of Affective Disorders.- Negative Symptoms of Schizophrenia: Methodological Issues, Biochemical Findings and Efficacy of Neuroleptic Treatment.- Interaction of Long-Term Antidepressant Treatment with Psychosocial Factors.

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