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Overview"Kniga posvyashchena kharakteristike yavleniya belkovoy nasledstvennosti, obnaruzhennogo v seredine 90-kh godov 20 veka u nizshikh eukariot. V osnove etogo fenomena lezhit konformatsionnoe prevrashchenie belkovoy molekuly, privodyashchee k vozniknoveniyu avtokataliticheski podderzhivaemogo konformera, nazyvaemogo prionom po analogii s infektsionnymi agentami belkovoy prirody mlekopitayushchikh, vyzyvayushchimi neizlechimye neyrodegenerativnye zabolevaniya. Naibolee izuchen s etoy tochki zreniya model'nyy geneticheskiy ob""ekt - drozhzhi-sakharomitsety, u kotorogo naydeno uzhe neskol'ko prionov. Issledovanie drozhzhevykh prionov imeet vazhnoe fundamental'noe znachenie, poskol'ku sushchestvenno rasshiryaet predstavleniya o mekhanizmakh nasledstvennosti. Krome togo, priony drozhzhey mogut sluzhit' v kachestve modeli dlya izucheniya molekulyarnykh mekhanizmov vozniknoveniya i podderzhaniya prionov u mlekopitayushchikh. Pomimo obshchey informatsii v knige podrobno opisana rabota, tsel'yu kotoroy bylo vyyasnenie prirody ranee neizvestnogo nekhromosomnogo nasledstvennogo determinanta drozhzhey." Full Product DetailsAuthor: Mironova Lyudmila , Rogoza Tat'yanaPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.70cm , Length: 22.90cm Weight: 0.186kg ISBN: 9783844357905ISBN 10: 3844357904 Pages: 120 Publication Date: 23 September 2011 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Language: Russian Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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