Human Toxicology of Chemical Mixtures

Author:   Harold Zeliger (Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator)
Publisher:   William Andrew Publishing
Edition:   2nd edition
ISBN:  

9781437734638


Pages:   574
Publication Date:   24 June 2011
Format:   Hardback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Human Toxicology of Chemical Mixtures


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Overview

In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author's focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are explained, as well as the body's methods of defending itself against xenobiotic intrusion. Part II examines the sources of the chemicals discusssed, looking at air and water pollution, food additives, pharmaceuticals, etc. Part III, which includes numerous case studies, examines specific effects of particular mixtures on particular body systems and organs and presents a theoretical framework for predicting what the effects of uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust recommended exposure levels for products containing mixtures. It also contains recommendations on how to limit exposure to mixtures in the products we use and on how to limit release of mixtures into the environment. Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive reference, a jumping off point for professionals (with extensive chapter bibliographies) and an introduction to the topic for those studying traditional toxicology. Addressing many inadequately understood illnesses and conditions such as asthma, infertility and cancer, it will also be of interest to health professionals, environmental scientists and lawyers.

Full Product Details

Author:   Harold Zeliger (Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator)
Publisher:   William Andrew Publishing
Imprint:   William Andrew Publishing
Edition:   2nd edition
Dimensions:   Width: 15.20cm , Height: 3.10cm , Length: 22.90cm
Weight:   0.890kg
ISBN:  

9781437734638


ISBN 10:   1437734634
Pages:   574
Publication Date:   24 June 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

PART I 1) Introduction to Chemical Toxicology of Mixtures 2) Health Effects of Exposures to Chemical Mixtures 3) Absorption of Chemical Mixtures 4) Chemical Toxicology PART II Exposures to Chemical Mixtures 5) Scope and sources of toxic exposures 6) In Utero Exposure 7) Air Pollution 8) Water Pollution 9) Soil Pollution 10) Food 11) Chemicals In and Around The Home 12) Sick Building Syndrome 13) Industrial Exposure 14) Pesticides 15) Alcohol and Tobacco: Recreational Toxins 16) Electromagnetic Radiation and Toxic Exposure PART III Mixture Effects on Body Systems 17) Respiratory System 18) Nervous System 19) Developmental Neurotoxicology 20) Autism: Effect of Maternal Exposure to Neurotoxic Chemcials 21) Attention Deficit Hyperactivity Disorder (ADHD) 22) Endocrine System 23) Toxic Infertility 24) Teratogens 25) Immune System 26) Chemical Sensitivity: Multiple Chemical Sensitivity (MCS) 27) Skin 28) Musculoskeletal System 29) Cardiovascular System 30) Liver 31) Kidneys 32) Cancer 33) Childhood Cancer 34) Cancer Clusters PART IV Regulatory Requirements 35) Regulatory Requirements 36) Conclusions and Recommendations

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Author Information

Dr. Harold I. Zeliger holds a Ph.D. in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger's research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.

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