Human Toxicology of Chemical Mixtures: Toxic Consequences Beyond the Impact of One-Component Product and Environmental Exposures

Author:   Harold Zeliger (Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator)
Publisher:   William Andrew Publishing
ISBN:  

9780815515890


Pages:   400
Publication Date:   25 July 2008
Replaced By:   9781437734638
Format:   Hardback
Availability:   Awaiting stock   Availability explained


Our Price $699.60 Quantity:  
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Human Toxicology of Chemical Mixtures: Toxic Consequences Beyond the Impact of One-Component Product and Environmental Exposures


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Overview

This book considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous and reproductive systems, as well as the various organs, including the kidneys, liver and skin. The author evaluates various sources of exposure, including air, water, and soil pollution; in utero exposure; chemicals contained in foods, cosmetics, and domestic cleaning products; adhesives and paints; industrial chemicals; pesticides; electromagnetic radiation; and chemicals ingested or inhaled during the use of alcohol, tobacco and narcotics. The book also examines the interplay between exposure to these mixtures and the prevalence of various diseases and conditions, including autism, attention deficit hyperactivity disorder (ADHD), developmental neurotoxicology, multiple chemical sensitivity (MSC), chronic fatigue syndrome (CFS), fibromyalgia (FM), Gulf war syndrome, cancer and cancer clusters. The author also discusses how exposure to these mixtures yields the above diseases and conditions in different populations: fetuses, infants, pre-adolescent children, adolescents and adults. Finally, the book addresses the profound policy implications for formulation, labeling and use of chemical products, and it proposes more stringent exposure limits and warning requirements in light of the newly recognized toxic effects that are directly attributable to the mixture of toxic lipophilic and hydrophilic chemicals.

Full Product Details

Author:   Harold Zeliger (Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator)
Publisher:   William Andrew Publishing
Imprint:   William Andrew Publishing
Dimensions:   Width: 15.20cm , Height: 3.80cm , Length: 22.90cm
Weight:   0.940kg
ISBN:  

9780815515890


ISBN 10:   0815515898
Pages:   400
Publication Date:   25 July 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9781437734638
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Awaiting stock   Availability explained

Table of Contents

PART I Introduction to Chemical Toxicology of Mixtures Introduction Health Effects of Exposures to Chemical Mixtures Absorption of Chemical Mixtures Chemical Toxicology PART II Exposures to Chemical Mixtures Scope and sources of toxic exposures In Utero Exposure Air Pollution Water Pollution Soil Pollution Food Chemicals In and Around The Home Sick Building Syndrome Industrial Exposure Pesticides Alcohol and Tobacco: Recreational Toxins Electromagnetic Radiation and Toxic Exposure PART III Mixture Effects on Body Systems Respiratory System Nervous System Developmental Neurotoxicology Autism: Effect of Maternal Exposure to Neurotoxic Chemcials Attention Deficit Hyperactivity Disorder (ADHD) Endocrine System Toxic Infertility Teratogens Immune System Chemical Sensitivity: Multiple Chemical Sensitivity (MCS) Skin Musculoskeletal System Cardiovascular System Liver Kidneys Cancer Childhood Cancer Cancer Clusters PART IV REGULATORY REQUIREMENTS, CONCLUSIONS Regulatory Requirements Conclusions

Reviews

An easy-to-read book that should be in any toxicologist's library. With an enormous effort of synthesis, the author has treated a wide variety of subjects in the emerging field of chemical mixtures. -- Arturo Ortego, M.D., School of Medicine and Health Sciences, Rovira I Virgili University, Reus, Spain


Author Information

Dr. Harold I. Zeliger holds a Ph.D. in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger's research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.

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