Overview

The ongoing debate on the use of DNA profiles to identify perpetrators in criminal investigations or fathers in paternity disputes has too often been conducted with no regard to sound statistical, genetic or legal reasoning. The contributors to this text have considerable experience in forensic science, statistical genetics or jurimetrics, and many of them have had to explain the scientific issues involved in using DNA profiles to judges and juries. Although the authors hold differing views on some of the issues, they have all produced accounts which pay due attention to the issues of independence of components of the profiles and of population substructures.

Full Product Details

Author:   B. Weir
Publisher:   Springer
Imprint:   Springer
Edition:   Reprinted from GENETICA 96:1-2, 1995
Volume:   4
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.809kg
ISBN:  

9780792335207

ISBN 10:   0792335201
Pages:   215
Publication Date:   30 September 1995
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.- The effect of relatedness on likelihood ratios and the use of conservative estimates.- The effects of inbreeding on DNA profile frequency estimates using PCR-based loci.- Correlation of DNA fragment sizes within loci in the presence of non-detectable alleles.- Inference of population subdivision from the VNTR distributions of New Zealanders.- Conditioning on the number of bands in interpreting matches of multilocus DNA profiles.- Match probability calculations for multi-locus DNA profiles.- Population genetics of short tandem repeat (STR) loci.- Assessing probability of paternity and the product rule in DNA systems.- The forensic debut of the NRC’s DNA report: population structure, ceiling frequencies and the need for numbers.- Applications of the Dirichlet distribution to forensic match probabilities.- The honest scientist’s guide to DNA evidence.- A comparison of tests for independence in the FBI RFLP data bases.- Alternative approaches to population structure.- DNA evidence: wrong answers or wrong questions?.- Subjective interpretation, laboratory error and the value of forensic DNA evidence: three case studies.- Exact tests for association between alleles at arbitrary numbers of loci.- A bibliography for the use of DNA in human identification.

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