Overview

This monograph presents information on the use of the immunodeficient C.B.-17 scid/scid mouse for studying human haematopoiesis in vivo. Because of the lack of both humoral and cellular immunity, this mouse can be a unique host for implantation of human haematopoietic tissue using different methods. In the first section, in vivo development of human haematopoietic stem cells and differentiation of human T cells are described. In addition, the effects of growth factors and toxic agents of human haematopoiesis are described. The second section contains chapters in which the human immune responses in the SCID mouse are reviewed. The third section covers SCID mouse models to study human infectious diseases, leukaemia's and genetic disorders.

Full Product Details

Author:   Maria-Grazia Roncarolo ,  Bruno Peault ,  Reiko Namikawa
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   illustrated edition
Weight:   0.825kg
ISBN:  

9783540590910

ISBN 10:   3540590919
Pages:   241
Publication Date:   06 July 1995
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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