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OverviewBehavioral and psychiatric genetics is a field of inquiry that has important implications for the nature of who we are. How Genes Influence Behavior is a unique introduction to behavioral genetics, which combines conceptual rigor with accessibility to outline both the substantial accomplishments of the field and the limitations and problems of interpretation. Offering unparalleled insights into how behavioural genetics is probed through real-world research, it considers evidence from humans and the major model organisms of mouse, fruit-fly and nematode worm to demonstrate how much of our current understanding of the genetic basis of human behavior stems from our exploration of other animals. Further, it uses these studies to connect the key themes of the book - the nature of gene action, and the inter-relationship of genetic and environmental influences on behaviour - across organisms, highlighting key commonalities and differences.The book also shows the major impact that neurobiology is having on our understanding of the field, to give a true depiction of behavioral genetics in the 21st century. However, care is taken throughout not to overwhelm the reader with scientific detail. Instead, the authors make the book fun to read without sacrificing accuracy or devaluing the complexity of the subject matter: they 'personalize' the science, mixing more standard narrative with biographical details to make the subject come alive. With the media filled with talk of the discovery of genes 'for' an array of human behaviors, there has never been a more pressing need for today's students - tomorrow's researchers - to be equipped with a clear, balanced view of the field. How Genes Influence Behavior is the perfect guide for all students, delivered in the words of three researchers who have witnessed first-hand the emergence of this fascinating field, and whose own investigations have been central to our current understanding of it. Full Product DetailsAuthor: Jonathan Flint (Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, UK.) , Ralph J. Greenspan (The Neurosciences Institute, San Diego, CA, USA.) , Kenneth S. Kendler (Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, VA, USA)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 18.90cm , Height: 1.30cm , Length: 24.50cm Weight: 0.571kg ISBN: 9780199559909ISBN 10: 0199559902 Pages: 264 Publication Date: 28 January 2010 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of Contents1: Introduction 2: Schizophrenia - All in the Family? 3: Molecular genetics - Linkage Analysis 4: Other Human Phenotypes - Genetic Influences on Alcoholism, Depression, and Personality 5: Genetic association analysis and candidate genes 6: Genome wide association studies 7: Model systems: Mice 8: Model systems: Genetic Variation in Flies and Worms 9: Model Systems: Circadian Rhythms 10: Model Systems: Neural Mechanisms of Learning and Memory 11: E Pluribus Unum, Ex Uno Plura: Reconciling Single Gene and Multigene Pictures of Behavior 12: MethodsReviews`This is an extremely accessible and fun to read textbook about molecular genetic research into behaviour and psychopathology. The authors have made great efforts to make the subject matter that can be 'scary' to students, very easy to read. Difficult concepts are explained clearly and the text is full of entertaining anecdotes that are likely to help the students remember the factual content of the chapters.' Dr Essi Viding, University College London `I found this informative and brilliantly-written. I think students will enjoy learning from this resource which is current, engaging and witty. Two of the best researchers in the field have come together to share their most interesting and exciting career-stories. ' Dr Alice Gregory, Goldsmiths, University of London `Without question, this is, by far, the best account for non-specialists of how genes influence behaviour. ' Michael Rutter, Psychological Medicine `These titans of research have crafted a helpful introduction to the relationship between genes and behavior, an introduction that is also unique for its interdisciplinary approach to genetic questions. ' Debby Tsuang and Andrew David, The American Journal of Psychiatry <br> Because of its general focus and casual style, How Genes Influence Behavior seems especially suited for beginning graduate students who are looking for supplementary reading on the basic concepts and methods of genetics, for something to whet their appetite as far as research is concerned. The book does its best to make the material easy to navigate. Throughout the chapters, the authors have included references to significant or landmark peer-reviewed articles and books, although, given the authors' own prolific repertoire of studies and manuscripts, a fair number of these references are to their own work, and each chapter concludes with helpful summaries of the most important points. How Genes Influence Behavior is an excellent primer for anyone with a hankering to discover more about what happens when man, rat, and fruit fly find themselves in the lab. -- Debby Tsuang, M.D., M.Sc.and Andrew David, B.A., Seattle, Wash. American Journal of Psychiatry<p><br> Because of its general focus and casual style, How Genes Influence Behavior seems especially suited for beginning graduate students who are looking for supplementary reading on the basic concepts and methods of genetics, for something to whet their appetite as far as research is concerned. The book does its best to make the material easy to navigate. Throughout the chapters, the authors have included references to significant or landmark peer-reviewed articles and books, although, given the authors' own prolific repertoire of studies and manuscripts, a fair number of these references are to their own work, and each chapter concludes with helpful summaries of the most important points. How Genes Influence Behavior is an excellent primer for anyone with a hankering to discover more about what happens when man, rat, and fruit fly find themselves in the lab. -- Debby Tsuang, M.D., M.Sc.and Andrew David, B.A., Seattle, Wash. American Journal of Psychiatry These titans of research have crafted a helpful introduction to the relationship between genes and behavior, an introduction that is also unique for its interdisciplinary approach to genetic questions. * Debby Tsuang and Andrew David, The American Journal of Psychiatry * Without question, this is, by far, the best account for non-specialists of how genes influence behaviour. * Michael Rutter, Psychological Medicine * I found this informative and brilliantly-written. I think students will enjoy learning from this resource which is current, engaging and witty. Two of the best researchers in the field have come together to share their most interesting and exciting career-stories. * Dr Alice Gregory, Goldsmiths, University of London * This is an extremely accessible and fun to read textbook about molecular genetic research into behaviour and psychopathology. The authors have made great efforts to make the subject matter that can be 'scary' to students, very easy to read. Difficult concepts are explained clearly and the text is full of entertaining anecdotes that are likely to help the students remember the factual content of the chapters. * Dr Essi Viding, University College London * Author InformationJonathan Flint is a Professor at the Wellcome Trust Centre for Human Genetics, Oxford University. He has extensive experience in molecular biology, molecular genetics, and rodent behavioural genetics with a specific focus on models of anxiety. Ralph Greenspan is based at the Neuroscience Institute in San Diego. He has studied the genetic foundations of many behaviours in Drosophila, and has analyzed naturally occurring genetic variations in its behaviour. Kenneth Kendler is a Professor at the Virginia Institute for Psychiatric and Behavioral Genetics at the Virginia Commonwealth University. He has conducted family and twin studies on a range of psychiatric and drug use disorders, and has conducted gene finding studies for schizophrenia, alcoholism, and drug dependence. Tab Content 6Author Website:Countries AvailableAll regions |
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