Overview

How did Seattle become home to some of the world's most influential infectious-diseases researchers? Hot Spot tells the story of young physician-scientists drawn to the off you go spirit of the Pacific Northwest. A University of Washington researcher discovered scores of new sexually transmitted pathogens and created a widely copied Seattle model to treat and prevent them. Another led clinical trials for the world's first antiviral therapy. Others found ways to protect immune-weakened patients from deadly infections after a bone marrow transplant. Such innovations put Seattle at the forefront of both the HIV/AIDS pandemic and the new field of global health. When COVID-19 emerged, Seattle was ready.

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Hot Spot captures the energy, intellectual curiosity, and collaborative spirit that marked me enormously during my time in Seattle. It brought back many memories of the larger-than-life personalities who inspired generations of scientists. -Peter Piot, former director, London School of Hygiene & Tropical Medicine; former executive director, UNAIDS.

Author Information

Mary Engel is an award-winning healthcare writer who has worked for newspapers in California, Alaska, and New Mexico and as a science writer for the Fred Hutchinson Cancer Research Center. The editorials she wrote for the Los Angeles Times were part of a 2005 Pulitzer Prize-winning series on mismanagement, malpractice, and racial injustice at a public hospital. She has been a Knight Science Journalism Fellow at MIT, a science journalism fellow at the Marine Biological Laboratory in Woods Hole, Mass., and a Salzburg Seminar Knight Media Fellow on multicultural healthcare in Salzburg, Austria. She lives in Seattle.

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