Overview

Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.

Full Product Details

Author:   G Singh Chhatwal
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2013 ed.
Volume:   368
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   5.207kg
ISBN:  

9783642363399

ISBN 10:   3642363393
Pages:   255
Publication Date:   20 March 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Group A Streptococcal Diseases and Their Global Burden.- Molecular Markers for the Study of Streptococcal Epidemiology.- Epidemiology and Pathogenicity of Zoonotic Streptococci.- Adherence and Invasion of Streptococci to Eukaryotic Cells and Their Role in Disease Pathogenesis.- Common Regulators of Virulence in Streptococci.- Host-Pathogen Interactions in Streptococcal Immune Sequelae.- Immunopathogenesis of Streptococcal Deep Tissue Infections.- Modulation of the Coagulation System During Severe Streptococcal Disease.- Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine.- Clinical Management of the Most Common Group A β-Hemolytic Streptococcal Infections.

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