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OverviewStreptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases. Full Product DetailsAuthor: G Singh ChhatwalPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: 2013 ed. Volume: 368 Dimensions: Width: 15.50cm , Height: 1.40cm , Length: 23.50cm Weight: 4.044kg ISBN: 9783642438363ISBN 10: 3642438369 Pages: 255 Publication Date: 12 April 2015 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsGroup A Streptococcal Diseases and Their Global Burden Anna P. Ralph and Jonathan R Carapetis Molecular Markers for the Study of Streptococcal Epidemiology David J McMillan, Martina L Sanderson-Smith, Pierre Smeesters and Kadaba S Sriprakash Epidemiology and Pathogenicity of Zoonotic Streptococci Marcus Fulde and Peter Valentin-Weigand Adherence and Invasion of Streptococci to Eukaryotic Cells and Their Role in Disease Pathogenesis Manfred Rohde and G. Singh Chhatwal Common Regulators of Virulence in Streptococci Nadja Patenge, Tomas Fiedler and Bernd Kreikemeyer Host-Pathogen Interactions in Streptococcal Immune Sequelae D. Patric Nitsche-Schmitz and Gursharan S. Chhatwal Immunopathogenesis of Streptococcal Deep Tissue Infections Linda Johansson and Anna Norrby-Teglund Modulation of the Coagulation System During Severe Streptococcal Disease Oonagh Shannon, Heiko Herwald and Sonja Oehmcke Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine Anna Henningham, Christine M. Gillen and Mark J. Walker Clinical Management of the Most Common Group A β-Hemolytic Streptococcal Infections Edward KaplanReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |