Overview

Liver disease has been identified as a leading cause of death in HIV-infected patients since the introduction of highly active antiretroviral therapy (HAART) in 1996. The HIV treatment community has been caught largely unaware of this emerging dilemma. Many HIV care providers are ill-equipped to understand and interpret liver injury patterns, or to provide comprehensive care and management for viral coinfections which they are not familiar with. HIV and Liver Disease provides a comprehensive update of the field covering the epidemiology, pathogenesis, management and treatment of liver disease in patients with HIV infection. The volume will help HIV care providers understand and interpret liver injury patterns, and/or provide comprehensive care and management for viral coinfections. Gastroenterologists and hepatologists will gain an understanding of complex drug regimens that are used to treat HIV and which may impact HCV and HBV treatment. Written by expert clinicians and researchers across multiple disciplines, HIV and Liver Disease will be of great value to gastroenterologists, hepatologists, infectious disease practitioners, as well as other health care providers who provide care or participate in research in the field of HIV.

Full Product Details

Author:   Kenneth E. Sherman
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2012 ed.
Weight:   0.812kg
ISBN:  

9781441917119

ISBN 10:   144191711
Pages:   209
Publication Date:   21 September 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- The HIV Epidemic in the United States - Current Trends, 2010.- Epidemiology of Liver Disease in Human Immunodeficiency Virus Infected Persons.- Current and Future  Treatment Guidelines for HIV.- Pathology of HIV-Associated Liver Disease.- Non-invasive Markers of Liver Injury and Fibrosis.- Mechanisms of Alcoholic Steatosis/Steatohepatitis.- Immunopathogenesis of Liver Injury.- Host Gene Polymorphisms and Disease/Treatment Outcomes in HIV and Viral Co-infections.- Effects of HIV on Liver Cell Populations.- HIV Replication.- Hepatitis C - Natural History.- Natural History of Hepatitis B Virus in HIV-Infected Patients.- Other Hepatitis Viruses and HIV Infection.- Hepatitis B Virus:  Replication, Mutation and Evolution.- Hepatitis C Virus Treatment in HIV.- Treatment of Hepatitis B in HIV-Infected Persons.- Prevention of Hepatitis Infection in HIV-Infected Patients.- Alanine Aminotransferase (ART) Hepatotoxicity.- Management of End Stage Liver Disease and the Role of Liver Transplantation in HIV infected Patients.- Assessment and Treatment of Alcohol and Substance Use Disorders in Patients with HIV Infection.- Racial Disparities in HIV and Liver Disease.- Quality of Life Issues in Patients with HIV and Liver Disease.

Reviews

From the reviews: In describing the close and growing relationship between HIV infection and liver disease, this book stresses the epidemiology and pathogenesis of liver disease in HIV and the mechanisms of coinfection with hepatitis viruses, with some chapters on the practical aspects of prevention and treatment. ! The author targets a broad audience of all healthcare practitioners involved in the care of HIV patients as well as specialists. Students and people interested in the mechanisms of disease, immunopathogenesis, will find this fascinating. (Cezarina Mindru, Doody's Review Service, March, 2012)

"From the reviews: ""In describing the close and growing relationship between HIV infection and liver disease, this book stresses the epidemiology and pathogenesis of liver disease in HIV and the mechanisms of coinfection with hepatitis viruses, with some chapters on the practical aspects of prevention and treatment. ... The author targets a broad audience of all healthcare practitioners involved in the care of HIV patients as well as specialists. Students and people interested in the mechanisms of disease, immunopathogenesis, will find this fascinating."" (Cezarina Mindru, Doody's Review Service, March, 2012) ""HIV and Liver Disease is well timed, because many patients coinfected with HIV and HCV have effective, stable control of their HIV but have not been so fortunate in controlling their HCV. The text can be appreciated by a wide audience ... most stimulating are the reviews describing the immunophysiology of the liver, with this organ functioning as 'Grand Central Station' for the antigen traffic from the portal vein resulting from disrupted intestinal epithelial integrity."" (Thomas Monson, Journal of the American Medical Association, Vol. 308 (4), July, 2012)"

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