Free Delivery Over $100
|
|
|||
|
||||
OverviewThe primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus. Full Product DetailsAuthor: Jay F. Storz (Susan J. Rosowski Professor of Biology, Susan J. Rosowski Professor of Biology, School of Biological Sciences, University of Nebraska, USA)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 19.00cm , Height: 1.30cm , Length: 24.80cm Weight: 0.588kg ISBN: 9780198810698ISBN 10: 0198810695 Pages: 256 Publication Date: 04 December 2018 Audience: Professional and scholarly , College/higher education , Professional & Vocational , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Active Availability: To order  Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of Contents1: Principles of protein structure 2: A study in scarlet: The role of hemoglobin in blood gas transport 3: Allosteric theory 4: Hemoglobin structure and allosteric mechanism 5: Evolution of the vertebrate globin gene family 6: Gene duplication and hemoglobin isoform differentiation 7: The evolution of novel hemoglobin functions and physiological innovation 8: Mechanisms of biochemical adaptation to environmental hypoxia 9: Darwin's molecule: Evolutionary insights into mechanisms of biochemical adaptation and protein evolutionReviewsAuthor InformationJay Storz is the Susan J. Rosowski Professor of Biology at the University of Nebraska. His research is motivated by questions about mechanisms of protein evolution, gene family evolution, and the genetic basis of biochemical and physiological adaptation. Professor Storz's work is supported by the National Institutes of Health and the National Science Foundation. Tab Content 6Author Website:Countries AvailableAll regions |
||||
