Overview

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hedgehog signaling.

Full Product Details

Author:   Gerald Litwack (Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States<br>Emeritus Professor, Rutgers University, United States)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   88
Dimensions:   Width: 15.20cm , Height: 2.80cm , Length: 22.90cm
Weight:   0.880kg
ISBN:  

9780123946225

ISBN 10:   0123946220
Pages:   584
Publication Date:   25 April 2012
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Hedgehog Signaling Siu Wah Choy, Shuk Han Cheng Canonical and Non-Canonical Hedgehog/GLI Signaling in Hematological Malignancies Fritz Aberger, Daniela Kern, Richard Greil and Tanja Nicole Hartmann Non-Canonical Hedgehog Signaling Donna Brennan, Xiaole Chen, Lan Cheng, My Mahoney, and Natalia A Riobo Gli Protein Nuclear Localization Signal Minoru Hatayama and Jun Aruga Mammalian Homologues of Drosophila Fused Kinase Alla Maloverjan and Marko Piirsoo Identification, Functional Characterization and Pathobiological Significance of GLI1 Isoforms in Human Cancers Richard L. Carpenter, Hui-Wen Lo Gli-Similar (Glis) Proteins: Their Mechanisms of Action, Physiological Functions, and Roles in Disease Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth, and Anton M. Jetten Sonic Hedgehog Regulates Wnt Activity During Neural Circuit Formation Nicole H. Wilson and Esther T. Stoeckli Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay Alberto Gulino, Lucia Di Marcotullio, Gianluca Canettieri, Enrico Desmaele, Isabella Screpanti Palmitoylation of Hedgehog Proteins John A. Buglino and Marilyn D. Resh Phosphorylation Regulation of Hedgehog Signaling Jianhang Jia Protein Kinase A Activity and Hedgehog Signaling Pathway Tomoya Kotani Phosphorylation of Gli by Camp-Dependent Protein Kinase Yoshinari Asaoka ZFP932 Suppresses Cellular Hedgehog Response and Patched1 Transcription G. Jason Huang, Zhenhua He and Liang Ma A New Era for an Ancient Drug; Arsenic Trioxide and Hedgehog Signaling Elspeth M. Beauchamp and Aykut Üren Aberrations and Therapeutics Involving the Developmental Pathway Hedgehog in Pancreatic Cancer Fergal Crothur Kelleher Sonic Hedgehog Signaling and Potential Therapeutic Indications Nicholas C. Bambakidis, Kaine Onwuzulike Sonic Hedgehog on Microparticles and Neovascularization Raffaella Soleti and Maria Carmen Martinez ‘Patch’-ing Up the Neurons: Revival or Enervation? Sayantani Ghosh, Arunabha Chakrabarti and Debashis Mukhopadhyay Activation of Hedgehog Pathway in Gastrointestinal Cancers Ling Yang, Xiulan Su, Jingwu Xie The Role Of Sonic Hedgehog as a Regulator of Gastric Function and Differentiation Rui Feng, Chang Xiao and Yana Zavros Sonic Hedgehog-Mediated Synergistic Effects Guiding Angiogenesis and Osteogenesis Sabine Fuchs, Eva Dohle, Charles James Kirkpatrick Hedgehog Inhibition as an Anti-Cancer Strategy G. Praveen Raju, and Diane Pham

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Author Information

Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.

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