Overview

The possible roles of heat shock proteins in normal development in animals, plants and model systems and the effects of elevated temperature on developmental programs are comprehensively treated. All relevant aspects of heat shock genes in normal and abnormal development are discussed, as are the major biological systems currently used to study the developmental biology of heat shock genes. Heat is a medically significant teratogen in humans and animals. The heat shock response itself is developmentally regulated and is likely to be protective in the developing embryo. In addition to roles in stress responses, heat shock genes are differentially expressed during normal development in germ tissues and in the specialized cell types of somatic tissues such as the mammalian brain. Heat shock genes are regulated during the cell cycle and heat shock promoters can be used in ectopic expression systems to study the functions of particular genes during development.

Full Product Details

Author:   Lawrence E. Hightower ,  Lutz Nover
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v. 17
Weight:   0.535kg
ISBN:  

9783540531197

ISBN 10:   354053119
Pages:   240
Publication Date:   06 December 1991
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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