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OverviewFull Product DetailsAuthor: Brock A. Peters , Radoje DrmanacPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 1st ed. 2023 Volume: 2590 Weight: 0.787kg ISBN: 9781071628188ISBN 10: 1071628186 Pages: 298 Publication Date: 07 November 2022 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsInterrogating the human diplome: computational methods, emerging applications, and challenges.- Targeted Locus Amplification and Haplotyping.- Full length transcript phasing with third generation sequencing.- Large scale complete sequencing and haplotyping of 1-10 kb DNA molecules using short massively parallel reads.- Accurate sequencing and haplotyping from 10 cells using Long Fragment Read (LFR) Technology.- Low-cost genome-scale phasing with barcode-linked sequencing.- A simple cost-effective method for whole genome sequencing, haplotyping, and assembly.- Read-based phasing and analysis of phased variants with WhatsHap.- Hapcut2, a method for phasing genomes using experimental data.- Determining complete chromosomal haplotypes by mLinker.- Haplotyping-assisted diploid assembly and variant detection with linked-reads.- Chromosome-length haplotypes with StrandPhaseR and Strand-seq.- Gamete-binning to achieve haplotype-resolved genome assembly.- Phasing DNA Methylation.- Analysis of 1276 haplotype-resolved genomes allows characterization of cis- and trans-abundant genes.- Phased genome assemblies.- Haplotype-assisted noninvasive prenatal diagnosis of genetic diseases by massively parallel sequencing of maternal plasma cell-free DNA.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |