Overview

The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology offers comprehensive, systematic coverage of the various techniques and methodologies currently available. Accomplished researcher Srinivas Aluru leads a team of experts from around the world to produce this groundbreaking, authoritative reference. With discussions ranging from fundamental concepts to practical applications, this book details the algorithms necessary to solve novel problems and manage the massive amounts of data housed in biological databases throughout the world. Divided into eight sections for convenient searching, the handbook covers methods and algorithms for sequence alignment, string data structures, sequence assembly and clustering, genome-scale computational methods in comparative genomics, evolutionary and phylogenetic trees, microarrays and gene expression analysis, computational methods in structural biology, and bioinformatics databases and data mining. The Handbook of Computational Molecular Biology is the first resource to integrate coverage of the broad spectrum of topics in computational biology and bioinformatics. It supplies a quick-reference guide for easy implementation and provides a strong foundation for future discoveries in the field.

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9781584884064

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Reviews

"“The material is well organized and documented, with good presentation and special care on typography. It is highly recommended for any researcher or graduate student interested in an insight into computational biology deeper than the practical use as “black boxes” of computer programs or web servers.” —Arturo Rojo-Dominguez, in Bulletin of Mathematical Biology, (2007) 69: 2775-2776 “It is to the credit of the author and publisher that they have been able to put together such a complete and well organized handbook this early. …Useful to the researcher looking for either an introduction to the field in general or go learn about areas outside his particular area of expertise.” —Books-On-Line ""...valuable to those new to the field as well as more experienced researchers. The handbook has done a good job of developing major areas in the field while maintaining a well-organized structure. The 'Handbook for Computational Molecular Biology' will be a great resource to those interested in this exciting field."" - Suzanne Sindi, Bioinformatics, Feb., 2007, Vol. 38, No. 3"

The material is well organized and documented, with good presentation and special care on typography. It is highly recommended for any researcher or graduate student interested in an insight into computational biology deeper than the practical use as black boxes of computer programs or web servers. -Arturo Rojo-Dominguez, in Bulletin of Mathematical Biology, (2007) 69: 2775-2776 It is to the credit of the author and publisher that they have been able to put together such a complete and well organized handbook this early. ...Useful to the researcher looking for either an introduction to the field in general or go learn about areas outside his particular area of expertise. -Books-On-Line ...valuable to those new to the field as well as more experienced researchers. The handbook has done a good job of developing major areas in the field while maintaining a well-organized structure. The 'Handbook for Computational Molecular Biology' will be a great resource to those interested in this exciting field. - Suzanne Sindi, Bioinformatics, Feb., 2007, Vol. 38, No. 3

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Srinivas Aluru

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