Overview

During the last few years there has been growing interest in the large family of GTPases structurally related to protooncogene product p21 ras. These proteins share structural similarities but are involved in a large spectrum of biological functions. While members of the ras subfamily regulate cell growth, rho proteins are implicated in the control of cytoskeletal organization in mammalian cells or in bud formation in yeast. Members of the ARF/SAR family are postulated to control vasicle budding, whereas Ypt1/Sec4/rab proteins are thought to regulate vesicle targeting and/or fusion. Owing to their functional divergence, the small GTPases have attracted the attention of many investigators in the fields of structural biology, cell biology, cell growth and differentiation and developmental biology. Numerous studies have contributed important data on the biochemical features, the intracellular focalisation, and in some cases, the function of these proteins. This book contains entries on almost 150 GTPases which have been identified so far, and the search has not yet been exhausted. This large repertoire of information is gathered together in an easy to consult format. This book is intended for research workers in the fields of cell biology, molecular biology, biochemistry, and cancer biology.

Full Product Details

Author:   Marino Zerial ,  Lukas A. Huber
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 18.00cm , Height: 3.30cm , Length: 24.00cm
Weight:   1.270kg
ISBN:  

9780198599456

ISBN 10:   0198599455
Pages:   496
Publication Date:   01 December 1995
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
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