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OverviewThis, the latest in the Sambrook and Tooze Guidebook Series enables non-specialists to rapidly gain access to unfamiliar work surrounding the secretory pathways. Detailing both the established and the experimental, this book outlines how recent work has established a role for the secretory pathway in the regulation of gene expression and cell-cycle control, clearly highlighting its importance. Addressing many aspects of the secretory pathway, the book contains almost two hundred entries, and falls in five sections: protein secretion in E.coli; translocation and maturation of newly synthesized polypeptides in the ER of eukaryotic cells; protein machines and catalyzing ER to golgi transport; membrane traffic in the golgi and to the cell surface, and membrane traffic to the lysosome/vacuole. Providing key references in a clear, informative layout, this book provides a valuable guide to the bewildering and complex array of genes and proteins involved in the cellular secretory pathway. The guidebook will maintain up to date entries - the almost two hundred contributors will update their entries continuously, and these updates will be available via the Internet. Full Product DetailsAuthor: Jonathan Rothblatt (Department of Biological Chemistry, Dartmouth College, Hanover) , Peter Novick (Department of Cell Biology, Yale University) , Tom H. Stevens (Institute of Molecular Biology, University of Oregon) , Randy SchekmanPublisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 19.00cm , Height: 2.00cm , Length: 24.50cm Weight: 0.777kg ISBN: 9780198599418ISBN 10: 0198599412 Pages: 316 Publication Date: 10 November 1994 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Out of Print Availability: In Print Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of Contents1. Protein secretion in E.coli ; 2. Translocation and maturation of newly-synthesized polypeptides in the ER of eukaryotic cells ; 3. Protein machines catalyzing ER to golgi transport ; 4. Membrane traffic in the golgi to the cell surface ; 5. Membrane traffic to the lysosome vacuoleReviewsthis book will be welcomed in labs working on the secretory pathway, as it is the firt such components guide to become available and will help us keep track of all the SECs, VPSs, PEPs and COPs Sean Munro, MRC Laboratory of Molecular Biology, TIBS, February 1995 The strength of the book is that it collects a vast amount of published data in a readily accessible form. If you keep getting lost among the thickets of membrane traffic, this guidebook will lead you to safety. Regis B. Kelly, University of California, San Francisco, Trends in Cell Biology, Vol 5, June 1995 '...a most convincing approach for rapid and thorough information...The different entries of the catalogues are written by leading specialists in the respective field and they are all impressive in their preciseness, clarity and information density. The volumes shold be present in every biochemical laboratory and other institutions in the field of molecular and cell biology.' G.Aumuller. '...a most convincing approach for rapid and thorough information...The different entries of the catalogues are written by leading specialists in the respective field and they are all impressive in their preciseness, clarity and information density. The volumes shold be present in every biochemical laboratory and other institutions in the field of molecular and cell biology.' * G.Aumuller. * The strength of the book is that it collects a vast amount of published data in a readily accessible form. If you keep getting lost among the thickets of membrane traffic, this guidebook will lead you to safety. * Regis B. Kelly, University of California, San Francisco, Trends in Cell Biology, Vol 5, June 1995 * this book will be welcomed in labs working on the secretory pathway, as it is the firt such components guide to become available and will help us keep track of all the SECs, VPSs, PEPs and COPs * Sean Munro, MRC Laboratory of Molecular Biology, TIBS, February 1995 * `this book will be welcomed in labs working on the secretory pathway, as it is the firt such components guide to become available and will help us keep track of all the SECs, VPSs, PEPs and COPs' Sean Munro, MRC Laboratory of Molecular Biology, TIBS, February 1995 `The strength of the book is that it collects a vast amount of published data in a readily accessible form. If you keep getting lost among the thickets of membrane traffic, this guidebook will lead you to safety.' Regis B. Kelly, University of California, San Francisco, Trends in Cell Biology, Vol 5, June 1995 `'...a most convincing approach for rapid and thorough information...The different entries of the catalogues are written by leading specialists in the respective field and they are all impressive in their preciseness, clarity and information density. The volumes shold be present in every biochemical laboratory and other institutions in the field of molecular and cell biology.'' G.Aumuller. Author InformationTab Content 6Author Website:Countries AvailableAll regions |