Overview

The text provides an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Integrated analysis, and systems biology * Experiment design * Interpretation of results * Automated analysis, Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

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"Steen Knudsen received his Ph.D. from the University of Copenhagen in 1990 and was among the pioneers of bioinformatics with a publication in Nature the same year. His postdoctoral training in bioinformatics at Harvard University concerned computational gene finding in the human genome. Since 1998 he has been working with methods for analysis of DNA microarray data. He currently heads the DNA microarray group at the Technical University of Denmark. Mark Schena co-authored the seminal paper on microarrays published in Science magazine in 1995. Dr. Schena was an honors biochemistry student with Dr. Daniel Koshland at UC Berkeley earning his B.A. in 1984, received his Ph.D. in 1990 with Dr. Keith Yamamoto in the Department of Biochemistry at UCSF, and performed postdoctoral research with Dr. Ronald Davis at Stanford University. He has authored more than 30 scientific papers, has given more than 80 lectures in 15 countries since 1995, and was featured as one of NOVA's ""Stars of Genomics."" Dr. Schena has consulted for more than 20 commercial organizations and is Chairman of the Board of NGS-ArrayIt, Inc., a genetic screening and diagnostics company. Dr. Schena is a Visiting Scholar at TeleChem/arrayit.com and resides with Rene Schena in Los Altos, California."

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