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OverviewGTPases are molecular switches that are used to control biochemical pathways. This book describes the properties and cellular roles of all the major families of GTPases: the G proteins, Ras, Rho, Rab, Arf, and Ran. All cells use GTPases to regulate the delivery of amino acids to the ribosome during protein synthesis, but eukaryotes, with their complex and compartmentalized environment, have exploited the versatility of GTPases to a much greater extent. The roles of two further families of GTPases in protein localization and protein tanslocation are discussed in chapter 8. Chapter 9 covers the huge amount of structural data accumulated for all families of GTPases and the proteins with which they interact. The final chapter describes the modification of GTPases by numerous bacterial toxins. It is not surprising, therefore, that GTPases have become a centre of attention for those studying the control of proliferation, differentiation, cell polarity, cell movement and vesicle and protein trafficking. GTPases: Frontiers in Molecular Biology provides a complete guide to this area and should be essential reading for cell and molecular biologists, biochemists and geneticists interested in these contemporary problems. Full Product DetailsAuthor: Alan Hall (MRC Laboratory for Molecular Biology, University College London)Publisher: Oxford University Press Imprint: Oxford University Press Volume: 24 Dimensions: Width: 19.30cm , Height: 2.60cm , Length: 25.30cm Weight: 0.655kg ISBN: 9780199637447ISBN 10: 019963744 Pages: 360 Publication Date: 20 January 2000 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of ContentsG proteins - I: Gs and Gi G proteins - II, Gz, G12 and Gz Ras Rho Rab Arf Ran GTPases in protein translocation and protein elongation The structure and function of molecular switches in three dimensions GTPases and bacterial toxinsReviewsAn extremely well laid out, comprehensive overview of the GTPase families ... an ideal reference for final year graduates Cell Biology International GTPases is a handy book ... will be a bible for people working on these aspects of signal transduction for many years to come Journal of Cell Science GTPases represents a successful attempt to gather in a handy, compact book a wealth of information about a field of rapid expansion ... GTPases will be of great utility not only for those interested in entering the field but also for the specialist TRENDS in Biochemical Sciences An extremely well laid out, comprehensive overview of the GTPase families ... an ideal reference for final year graduates Cell Biology International GTPases is a handy book ... will be a bible for people working on these aspects of signal transduction for many years to come Journal of Cell Science GTPases represents a successful attempt to gather in a handy, compact book a wealth of information about a field of rapid expansion ... GTPases will be of great utility not only for those interested in entering the field but also for the specialist TRENDS in Biochemical Sciences Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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