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OverviewThis title describes the work behind a major discovery: the establishment of a new pathway that specifically regulates the female meiosis, a process essential for sexual reproduction. It chronicles a new gene mapping method and the cloning and documentation of several types of genes that were proven to have significant influence on the cell cycle. It should be of interest to anyone doing work with fruit flies, both graduate students and principal investigators. Full Product DetailsAuthor: Bin ChenPublisher: Springer Imprint: Springer Edition: 2001 ed. Dimensions: Width: 15.50cm , Height: 0.70cm , Length: 23.50cm Weight: 0.730kg ISBN: 9780792373636ISBN 10: 0792373634 Pages: 80 Publication Date: 31 May 2001 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsGeneral introduction.- 1. Female meiotic cell cycle.- 2. Genesis and meiosis in drosophila females.- 3. Cell cycle regulation of Drosophila female meiosis.- 4. Mutations in grauzone (grau) and cortex(cort) block progression of drosophila female meiosis and cause other defects.- 5. Goals and significance of this dissertation research.- Mapping of drosophila mutations using site-specific male recombination.- 1. Introduction.- 2. Materials and Methods.- 3. Results.- 4. Discussion.- Completion of meiosis in drosophila oocytes requires transcriptional control by grauzone, a new zinc finger protein.- 1. Introduction.- 2. Experimental Procedures.- 3. Results.- 4. Discussion.- 5. Acknowledgements.- Conclusions and Considerations.- 1. Drosophila as a model to study regulation of female meiotic cell cycle.- 2. Grau and cort are two members of a new pathway that regulates the meiotic cell cycle machinery in drosophila females.- 3. Male recombination mapping is a general method to map drosophila autosomal mutations.- References.ReviewsAuthor InformationBin Chen is a researcher at Stanford University and is the winner of the Larry Sandler Award. Tab Content 6Author Website:Countries AvailableAll regions |