Overview

Goldfrank’s is the premier toxicology textbook that should be in every emergency department or poison center library. Whether you are a student, resident, or faculty, there is something here for you. If you are a toxicology fellow or poison specialist studying for your boards, this is your go-to book. I highly recommend this work… —The Journal of Emergency Medicine The best edition yet of the landmark text in medical toxicology A Doody’s Core Title for 2022! Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins. Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations. The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis. New to this Edition: •  Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes •  New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies •  New content on toxicogenomics explores its increasingly important role in predictive toxicology •  Chapter-ending bulleted summaries of key points  •  Updated coverage of synthetics such as “K2” •  Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools  

Full Product Details

Author:   Lewis Nelson ,  Mary Howland ,  Mary Ann Howland ,  Neal Lewin
Publisher:   McGraw-Hill Education
Imprint:   McGraw-Hill Education
Edition:   11th edition
Dimensions:   Width: 22.60cm , Height: 6.90cm , Length: 28.20cm
Weight:   4.312kg
ISBN:  

9781259859618

ISBN 10:   1259859614
Pages:   4
Publication Date:   27 March 2019
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   In stock  
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Table of Contents

1.                Historical Principles and Perspectives           Paul M. Wax   2.                Toxicologic Misfortunes and Catastrophes in History           Paul M. Wax   PART A THE GENERAL APPROACH TO THE PATIENT   3.                Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes           Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman   4.                Principles of Managing the Acutely Poisoned or Overdosed Patient           Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman [include eCPR, critical care dispositions]   SC1.    Principles of Antidote Stocking           [Insert author(s)]   5.                Decontamination Principles: Prevention of Gastrointestinal Absorption           Lotte C. G. Hoegberg and Anne-Bolette Gude   SC2.    Decontamination Principles: Prevention of Dermal, Inhalational and Ocular    Absorption           [Insert author(s)]   A1.      Activated Charcoal           Silas W. Smith and Mary Ann Howland       A2.      Whole-Bowel Irrigation and Other Intestinal Evacuants           Silas W. Smith and Mary Ann Howland   6.                Principles and Techniques Applied to Enhance Elimination           David S. Goldfarb and Marc Ghannoum   7.                Laboratory Principles           Petrie M. Rainey   8.                Principles of Diagnostic Imaging           David T. Schwartz   9.                Pharmacokinetic and Toxicokinetic Principles           Mary Ann Howland     PART B THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY        SECTION I    BIOCHEMICAL AND MOLECULAR CONCEPTS   10.            Chemical Principles           Stephen J. Traub and Lewis S. Nelson   11.            Biochemical and Metabolic Principles           Kurt C. Kleinschmidt and Kathleen A. Delaney   12.            Fluid, Electrolyte, and Acid–Base Principles           Alan N. Charney and Robert S. Hoffman   13.            Neurotransmitters and Neuromodulators           Steven C. Curry, Ayrn D. O’Connor, Kimberlie A. Graeme, Kirk C. Mills, and Aaron B. Skolnik   14.            Withdrawal Principles           Richard J. Hamilton and [new author]   SECTION II PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS   15.            Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles           Cathleen Clancy   16.            Cardiologic Principles II: Hemodynamics [new author] and Robert A. Hessler   17.            Dermatologic Principles           Jesse M. Lewin, Neal A. Lewin, and Lewis S. Nelson        SC3.    Transdermal Toxicology Lewis S. Nelson   18.            Gastrointestinal Principles           Matthew D. Zuckerman and Richard J. Church   19.            Genitourinary Principles           Jason Chu   20.            Hematologic Principles           Marco L.A. Sivilotti     21.            Hepatic Principles           Kathleen A. Delaney   22.            Neurologic Principles           Rama B. Rao   23.            Oncologic Principles Richard Wang   24.            Ophthalmic Principles           Adhi Sharma   25.            Otolaryngologic Principles [new author] and William Chiang   26.            Psychiatric Principles           Erin A. Zerbo and Andr ea M. Kondracke   27.            Renal Principles           Marc Ghannoum and David S. Goldfarb   28.            Respiratory Principles           Andrew Stolbach and Robert S. Hoffman   29.            Thermoregulatory Principles           Susi U. Vassallo and Kathleen A. Delaney   SECTION III SPECIAL POPULATIONS   30.            Reproductive and Perinatal Principles           Jeffrey S. Fine   31.            Pediatric Principles           Jeffrey S. Fine   32.            Geriatric Principles           Judith C. Ahronheim and Mary Ann Howland   PART C THE CLINICAL BASIS OF MEDICAL TOXICOLOGY   SECTION I A. ANALGESICS AND ANTIINFLAMMATORY MEDICATIONS   Case Study 1   33.            Acetaminophen           Robert G. Hendrickson       A3.      N-Acetylcysteine            Robert G. Hendrickson and Mary Ann Howland   34.            Colchicine, Podophyllin, and the Vinca Alkaloids           Joshua G. Schier   35.            Nonsteroidal Antiinflammatory Drugs           William J. Holubek   36.            Opioids           Lewis S. Nelson and Dean Olsen        A4.      opioid antagonists           Lewis S. Nelson and Mary Ann Howland   SC4.    Internal Concealment of Xenobiotics           Jane M. Prosser   SC5.    Harm Reduction for Opioid Overdose           ?Josh Lee   37.            Salicylates           Daniel M. Lugassy   A5.      sodium bicarbonate Paul M. Wax     B. Food, Diet, and Nutrition   CASE STUDY 2   38.            Botulism           Howard L. Geyer   A6.      botulinum antitoxin           Silas W. Smith and Howard L. Geyer   39.          Food Poisoning [new author]and Michael Tunik   40.            Dieting Xenobiotics and Regimens           Jeanna M. Marraffa   41.            Athletic Performance Enhancers Susi U. Vassallo   42.            Essential Oils Lauren Kornreich Shawn   43.            Herbal Preparations [new author] and Oliver Hung   44.          Vitamins           Beth Y. Ginsburg   45.            Iron           Jeanmarie Perrone        A7.      deferoxamine Mary Ann Howland   C. pharmaceuticals   case study 3   46.            Pharmaceutical Additives Sean P. Nordt and Lisa E. Vivero   47.            Antidiabetics and Hypoglycemics/Antiglycemics           George M. Bosse   A8.      Dextrose (d-Glucose) [new author] and Larissa Velez   A9.      octreotide           Mary Ann Howland and Silas W. Smith   48.            Antiepileptics           Suzanne Doyon   A10.    l-carnitine           Mary Ann Howland   49.            Antihistamines and Decongestants           Sophie Gosselin   A11.    physostigmine salicylate           Mary Ann Howland   50.            Chemotherapeutics           Richard Y. Wang   51.            Methotrexate, 5-Flourouracil, and Capecitabine          Richard Y. Wang   A12.    folates: leucovorin (Folinic acid) and Folic Acid           Mary Ann Howland   A13.    glucarpidase (carboxypeptidase g2)           Silas W. Smith   A14.    uridine triacetate           Silas W. Smith   SC6.    Inadvertent Intrathecal Administration of Xenobiotics           Rama B. Rao   SC7.    Extravasation of Chemotherapeutics Richard Y. Wang   52.            Antimigraine Medications Jason Chu   53.            Thyroid and Antithyroid Medications           Nicole C. Bouchard   D. Antimicrobials   54.            Antibacterials, Antifungals, and Antivirals Christine M. Stork   55.            Antimalarials           James David Barry   56.            Antituberculous Medications           Christina H. Hernon        A15.    pyridoxine           Mary Ann Howland   E. Cardiopulmonary Medications   CASE STUDY 4   57.            Antidysrhythmics           Lewis S. Nelson   A16.    Magnesium Sulfate           Silas Smith   58.            Antithrombotics           Betty C. Chen and Mark Su   A17.    Protein Complex Concentrate and novel Antithrombotic Antidotes           [Insert author(s)], Betty Chen and Mark Su   A18.    Vitamin k1           Mary Ann Howland   A19.    protamine Mary Ann Howland   59.            β-Adrenergic Antagonists           Jeffrey R. Brubacher   A20.    Glucagon           Mary Ann Howland   60.            Calcium Channel Blockers           David H. Jang and Francis Jerome DeRoos   A21.    High-dose insulin euglycemia           Samuel J. Stellpflug and William Kerns, II   61.            Miscellaneous Antihypertensives and Pharmacologically Related Agents Francis Jerome DeRoos   62.            Cardioactive Steroids           Jason B. Hack   A22.    digoxin-specific antibody fragments           Mary Ann Howland   63.            Methylxanthines and Selective β2-Adrenergic Agonists           Robert J. Hoffman     F. ANESTHETICS AND RELATED MEDICATIONS   64.            Local Anesthetics           David R. Schwartz and Brian Kaufman   A23.    intravenous lipid emulsion           [new author] and Todd Bania   65.            Inhalational Anesthetics           Brian Kaufman   66.            Neuromuscular Blockers           Kenneth M. Sutin   A24.    dantrolene sodium Kenneth M. Sutin   A25.    Sugammadex [new; Author]   G. Psychotropics   CASE STUDY 5   67.            Antipsychotics           David Juurlink   68.            Cyclic Antidepressants           Erica L. Liebelt   69.            Serotonin Reuptake Inhibitors and Atypical Antidepressants           Christine M. Stork   70.            Lithium           Howard A. Greller   71.            Monoamine Oxidase Inhibitors           Alex F. Manini   72.            Sedative-Hypnotics           David C. Lee   A26.    flumazenil           Mary Ann Howland   H. SUBSTANCES OF ABUSE   CASE STUDY 6   73.            Amphetamines          ;  David H. Jang   74.            Cannabinoids           Jeff M. Lapoint   75.            Cocaine           Jane M. Prosser and Robert S. Hoffman   A27.     Benzodiazepines           Robert S. Hoffman, Lewis S. Nelson, and Mary Ann Howland   76.            Ethanol           Luke Yip   A28.    Thiamine hydrochloride           Robert S. Hoffman   77.            Ethanol Withdrawal           Jeffrey A. Gold and Lewis S. Nelson   78.            Disulfiram and Disulfiram-like Reactions           Amit K. Gupta   79.            <

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Mary Ann Howland, PharmD, DABAT, FAACT Clinical Professor of Pharmacy, St. Johns University College of Pharmacy; Consultant, Department of Emergency Medicine, Bellevue Hospital Center and New York University Medical Center; Senior Consultant in Residence, New York City Poison Center, New York, New York. McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

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