Overview

Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life.  Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms.  Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition.  This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.

Full Product Details

Author:   Tim Schedl
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Volume:   757
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   6.672kg
ISBN:  

9781489993533

ISBN 10:   1489993533
Pages:   432
Publication Date:   20 September 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Introduction to germ cell development in C. elegans.- Germ cell specification.- Sex determination in the C. elegans germline.- Stem cell proliferation versus meiotic fate decision in C. elegans.- Physiological control of germline development.- Meiotic development in C. elegans.- Spermatogenesis.- Translational control in the C. elegans germ line.- Germ cell apoptosis and DNA damage responses.- Control of Oocyte Growth and Meiotic Maturation in C. elegans.- Fertilization.- The oocyte-to-embryo transition.- Epigenetic Control of Germline Development.- Using Caenorhabditis to explore the evolution of the germ line.- Index.

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