Overview

Genome analysis has undergone a period of explosive growth in recent years. This book describes up-to-date methods for genome mapping, arranged in order of increasing resolution, from linkage analysis to restriction mapping. Topics covered include linkage mapping of human, animal, and plant genomes; mapping of quantitative trait loci; radiation hybrid mapping; HAPPY mapping; somatic cell hybrids; flow-sorted and microdissected chromosomes; fluorescence in situ hybridization; contig assembly; chromosome walking; and long-range restriction mapping. Two appendices describe sources of freely available biological and computational resources relevant to genome analysis.

Full Product Details

Author:   Paul H. Dear (MRC Laboratory for Molecular Biology, Cambridge)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   184
Dimensions:   Width: 15.60cm , Height: 2.20cm , Length: 23.50cm
Weight:   0.691kg
ISBN:  

9780199636303

ISBN 10:   0199636303
Pages:   396
Publication Date:   21 August 1997
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

1: Human linkage mapping 2: Linkage mapping of plant and animal genomes 3: Linkage mapping of quantitative trait loci in plants and animals 4: Radiation hybrid mapping 5: HAPPY mapping 6: Construction and use of somatic cell hybrids 7: The use of flow-sorted chromosomes in genome mapping 8: The use of microdissected chromosomes in genome mapping 9: Fluorescence in situ hybridization 10: Contig assembly by fingerprinting 11: Chromosome wallking 12: Long-range restriction mapping of genomic DNA Appendix 1 Core list of suppliers Appendix 2 Non-commercial source for genome mapping Appendix 3 Bioinformatics for genome mapping

Reviews

This book is part of a large series of instruction manuals on diverse topics in biochemistry and molecular biology. The 12 individually authored chapters in this volume contain practices and protocols of interest to the advanced researcher in the field of genome mapping. Each chapter contains an introduction, lists of materials, references, and several protocols. The text is indexed and illustrated with tables and figures, some of which are in color. A list of abbreviations is provided. -- Biosis, Vol 50, Issue 9, Sept 22, 1998<br>

This book is part of a large series of instruction manuals on diverse topics in biochemistry and molecular biology. The 12 individually authored chapters in this volume contain practices and protocols of interest to the advanced researcher in the field of genome mapping. Each chapter contains an introduction, lists of materials, references, and several protocols. The text is indexed and illustrated with tables and figures, some of which are in color. A list of abbreviations is provided. -- Biosis, Vol 50, Issue 9, Sept 22, 1998

Author Information

Dr Paul Dear, MRC Centre, Hills Road, Cambridge CB2 2QH. Email: phd@mrc-lmb.cam.ac.uk. Tel: 01223 402190. Fax: 01223 412178

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