Overview

"In the years since the publication of Susumu Ohno's 1970 book ""Evolution by Gene Duplication"" tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until modern methodological advances. This book evaluates empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation."

Full Product Details

Author:   Axel Meyer ,  Yves van de Peer
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2003 ed.
Dimensions:   Width: 21.00cm , Height: 1.60cm , Length: 27.90cm
Weight:   0.965kg
ISBN:  

9781402010217

ISBN 10:   1402010214
Pages:   237
Publication Date:   30 April 2003
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Early events in genome evolution.- 1. Gene duplication and other evolutionary strategies: from the RNA world to the future.- 2. Major transitions in evolution by genome fusions: from prokaryotes to eukaryotes, metazoans, bilaterians and vertebrates.- 3. Detection of gene duplications and block duplications in eukaryotic genomes.- 4. The evolutionary demography of duplicate genes.- Debating the 2R and 3R genome duplication hypotheses.- 5. Functional evolution in the ancestral lineage of vertebrates or when genomic complexity was wagging its morphological tail.- 6. Numerous groups of chromosomal regional paralogies strongly indicate two genome doublings at the root of the vertebrates.- 7. Are all fishes ancient polyploids?.- 8. More genes in vertebrates?.- 9. 2R or not 2R: Testing hypotheses of genome duplication in early vertebrates.- 10. The 2R hypothesis and the human genome sequence.- Plant genome evolution.- 11. Introns in, introns out in plant gene familes: a genomic approach of the dynamics of gene structure.- 12. Investigating ancient duplication events in the Arabidopsis genome.- Case studies.- 13. Crystallin genes: specialization by changes in gene regulation may precede gene duplication.- 14. Evolution of signal transduction by gene and genome duplication in fish.- 15. The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters.- 16. Dopamine receptors for every species: Gene duplications and functional diversification in Craniates.- 17. Nuclear receptors are markers of animal genome evolution.- 18. The fates of zebrafish Hox gene duplicates.- 19. Phylogenetic analysis of the mammalian Hoxc8 non-coding regon.- Gene networks and evolution.- 20. Maximum likelihood methods for detecting adaptive evolution after geneduplication.- 21. Approach of the functional evolution of duplicated genes in Saccharomyces cerevisiae using a new classification method based on protein-protein interaction data.- 22. Developmental gene networks and evolution.- Index of Authors.- Index of Keywords.

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