Overview

This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader’s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases. The textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics.

Full Product Details

Author:   Ju Han Kim
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2019
Weight:   0.796kg
ISBN:  

9789811319419

ISBN 10:   9811319413
Pages:   367
Publication Date:   10 May 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION.- Chapter 1. Bioinformatics For Life.- Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis.- Chapter 3. Personal Genome Data Analysis.- Chapter 4. Personal Genome Interpretation and Disease Risk Prediction.- Part 2. ADVANCED MICROARRAY DATA ANALYSIS.- Chapter 5. Advanced Microarray Data Analysis.- Chapter 6. Gene Expression Data Analysis.- Chapter 7. Gene Ontology and Biological Pathway-based Analysis.- Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction.- Chapter 9. MicroRNA Data Analysis.- Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS.- Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics.- Chapter 11. Motif and Regulatory Sequence Analysis.- Chapter 12. Molecular Pathways and Gene Ontology.- Chapter 13. Biological Network Analysis.- Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS.- Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations.- Chapter 15. SNP Data Analysis.- Chapter 16. GWAS Data Analysis.- Chapter 17. CNV Data Analysis.- Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS.- Chapter 18. Metagenome and Epigenome Data Analysis.- Chapter 19. Metagenome Data Analysis.- Chapter 20. Epigenome Databases and Tools.- Chapter 21. Epigenome Data Analysis.- Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS.- Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE.

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Author Information

Professor. Ju Han Kim, Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul , South Korea.

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