Overview

With the decoding of whole genome sequences of many organisms, new vistas of research have emerged in computational biology. The scientific community has free access to the genome sequence data from the public databases. It is often hard to make sense of these huge data of DNA and protein sequences. Therefore, bioinformatics tools are used to handle, store and analyse genome sequence data. This book first discusses how whole genome sequences are generated by using high throughput DNA sequencing technologies, before covering the storing of sequences in biological databases. It then covers the basic principals involved in sequence analysis and softwares applications, and offers practical exercises. Data mining approaches for the discovery of genes and DNA markers are also discussed. A glossary of important terms and an introduction to basic bioinformatics software is included. The book will serve as a textbook for B.Tech (bioinformatics and biotechnology) students and will be useful reference book for postgraduate students and research scientists working in the life sciences, genomics, biotechnology and molecular biology.

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9789380026367

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