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OverviewThe objective of this book is to review the impact of genetic variation on risk of human disease at the different major levels of organization: cells, individuals, families, and populations. The volume begins with a discussion of sources and rates of mutation which ultimately give rise to the vast amount of extant genetic variation. This is followed by presentations of current understanding of how genetic variation is maintained within and among populations. The volume ends with discussions of the implications of such variation for understanding the evolution of our species. This collection gives an unusually broad treatment of the subject, with chapters from some of the leading workers in the field. James Neel's chapter on human consanguinity effects and M. Otake's on the genetic effects of radiation associated with the dropping of the Hiroshima and Nagasaki atomic bombs should be singled out for special emphasis. As an up-to-date overview of ongoing research, this work will be of interest to a wide range of workers in the fields of human population genetics, evolution, and epidemiology. Full Product DetailsAuthor: Charles F. Sing (Professor of Human Genetics, University of Michigan Medical School) , Craig L. Hanis (Center for Demographic and Population Genetics, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston)Publisher: Oxford University Press Inc Imprint: Oxford University Press Inc Dimensions: Width: 16.00cm , Height: 2.30cm , Length: 24.10cm Weight: 0.697kg ISBN: 9780195066258ISBN 10: 0195066251 Pages: 318 Publication Date: 17 June 1993 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: To order  Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of ContentsReviewsMost geneticists will find both useful and interesting material in this volume because of its great breadth and the quality of the authors. William G. Hill, University of Edinburgh, Genetical Research, Volume 64 - 1994 Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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